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Women with many children, especially more than four or five, may seem older than multiple pregnancies can accelerate cell aging, said a new study.
According to the researchers, there is good evidence to show that more children can increase the risk of certain diseases and shorten their lifespan.
Cellular aging was accelerated from six months to two years for each additional pregnancy.
"Our study highlights cellular changes during pregnancy, possibly related to adaptive changes in the mother's immune system as a possible explanation," said Christopher Kuzawa. For the study, published in the journal Scientific Reports, the team collected data from some 3,200 women aged 20 to 22 years, examining two distinct markers of cellular aging, namely telomere. "Telomere length and epigenetic age are cellular markers that independently predict mortality, and both seemed" older "in women who had more pregnancies in their reproductive history." "Even after taking into account other factors that affect cell aging, the number of pregnancies still came in first," added Ryan
. The paradox was that a woman's biological age was higher with every child she had, if a woman was pregnant when the measurements were taken, her epigenetic age, and to a lesser extent her telomeres, seemed "younger" than expected for its chronological age, "said Kuzawa.
"It is an interesting situation in which pregnancy temporarily gives the impression of being young, but there seems to be a lasting and cumulative relationship between the number of pregnancies and the number of pregnancies. accelerated biological age, "noted Kuzawa.
IANS
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