Psychiatric stress-related condition may increase the risk of autoimmune disease



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Stress is known to cause physiological changes, including changes in immune function, but the evidence linking it to specific diseases is limited.

This study uses JAMA a Swedish database of 106,464 patients with post-traumatic stress disorder (PTSD), acute stress response, or maladaptation disorder. They compared them to 1,064,640 people without stress-related disorders and to 126,652 of their stress-free siblings.

During a 10-year average follow-up period, 8,284 cases of autoimmune diseases were diagnosed with a stress disorder; After controlling for other risk factors, they found that compared to those who had not experienced severe stress, those with a stress disorder were 36% more likely to have autoimmune disease and 29 % more likely than their unstressed brothers and sisters. People with a diagnosis of PTSD were at particularly high risk – they were 46% more likely to develop an autoimmune disease.

"Stress really affects health in the long run," said lead author Dr. Huan Song, a postdoctoral fellow at the University of Iceland. "It not only affects psychiatric health, but leaves people vulnerable to other diseases.There are many treatments now available for stress-related disorders, and it is important that people receive early treatment," he said. he said.

New York Times

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