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How to protect a mutation from pain, wounds and fears
A Scottish retiree seems to have a lot in common with the superheroes of Marvel's current movies. The old lady feels almost no pain and has an extremely strong ability to heal wounds. Researchers have now discovered that the extraordinary ability of the woman is due to a mutation.
A recent study from University College London and Oxford University, universally respected, revealed that this 71-year-old Scottish woman was practically unmutated and could heal. his wounds very quickly, often without leaving scars. The results of the study were published in the British journal "British Journal of Anesthesia".
A woman has noticed burns especially by her smell
The victim reported many burns and cuts without pain. She often smelled burnt meat even before she noticed the injury. According to the researchers, indolence and superhuman healing are due to a genetic mutation not previously described. The case could open the door to a range of new treatments that help people better recover after surgery and overcome chronic pain and anxiety disorders.
Researchers became aware of hip replacement mutation
Jo Cameron drew the attention of doctors for the first time when she was treated for a hip problem at the age of 65. The hip was then clbadified as arthritic and had to be replaced. The patient did not respond as expected to the disabling procedure and, after a second pain-free surgery, the physicians decided that the case needed to be examined more closely.
Wounds usually heal without scarring
In addition to her detailed medical history, the patient reported numerous burns and cuts without pain. The resulting wounds or burns healed exceptionally quickly and there was only a very small scar, or none at all. The old lady did not realize that she was so different from others before needing a hip replacement. A few years ago, the woman simply did not know that it was unusual to feel so little pain. The affected person was of the opinion that it was completely normal.
FAAH-Out closes an important gene in the patient
In their study, researchers from University College London and the University of Oxford identified two notable mutations in the patient. One of the mutations was a gene called FAAH (fatty acid amide hydrolase). The FAAH gene plays a role in the body's endocannabinoid system, the parts of the central nervous system that play an important role in pain, memory, and mood, and on which cannabis compounds act. They also found a second gene that was previously considered a useless DNA. It now appears that this gene, called FAAH-Out, controls the Faah gene and stops it at Mrs. Cameron's.
Patients were not afraid and never panicked
In addition to increasing wound healing and resistance to pain, the woman has achieved exceptional results in anxiety and depression tests. She explained that she never panics in dangerous situations, such as a car accident.
Insights could protect people from pain in the future
The effects of these results are immense, explain the authors of the study. Half of patients who recover from an operation still have moderate to severe pain despite modern painkillers. The so-called FAAH-out might be the key to unleashing the FAAH gene's pain-reducing potential if other treatments have already failed. The findings suggest a new badgesic finding that could provide relief from postoperative pain and could also accelerate wound healing. Hopefully the new discoveries will help 330 million patients undergoing a global operation every year, according to the research team. The old lady was delighted that her genetic mutation could help other sufferers. (As)
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