15h20 – Preventive treatment against HIV: very encouraging results

Anti-HIV preventive treatment (PrEP) has, in one year in the Paris region, a total effectiveness, with zero infections. This is indicated by preliminary results presented Tuesday at the International AIDS Conference in Amsterdam. Pre-exposure prophylaxis, which consists of taking the drug Truvada or its generics, is intended for people at risk. The National Agency for Research on AIDS (ANRS) and the Public Assistance-Hospitals of Paris (AP-HP) follow 1,435 volunteers "recruited between May 3, 2017 and May 1, 2018". "To date, no case of HIV infection has been observed," the institutions wrote in a statement, when presenting the results in Amsterdam. Another encouraging result: "There has been, so far, no discontinuation of the study for reasons related to adverse effects of treatment." This study confirms that the drug is very well tolerated. Truvada is a simple tablet to choose from every day (which is 44% of volunteers in this study) or in anticipation of badual activity (53% of volunteers). This preventive use is not his first indication: initially, this drug combining two antiretrovirals was intended for HIV-positive people. It has benefited in France from a temporary recommendation of use for its preventive use in 2016, then from a marketing authorization in 2017. The group of the volunteers is composed "for the moment essentially of men having reports bad with men, "said ANRS and AP-HP. Researchers would like to "also recruit volunteers from other populations such as transgender people and heterobadual men and women at high risk of HIV infection," said one of them, Jean-Michel Molina (Saint -Louis of Paris). (SDA / uc) (Belga)

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