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This could be an important step in the fight against HIV. Researchers said Saturday they developed an experimental vaccine that provoked an immune response in humans and protected macaques from infection. "These results represent a milestone," study director Virologist Dan Barouch said in a statement from The Lancet.
If the development of this vaccine is now advanced enough to launch a test on 2,600 women in southern Africa, the researcher remains measured and recalls that there was no guarantee that the following tests would be so positive. "We must remain cautious," he told AFP. However, this test is a real hope: "It will be only the fifth concept of vaccine against HIV whose effectiveness will be tested in the 35 years and a few history of the epidemic," said Dan Barouch. [19659003] The study released this Saturday details vaccine test results in 393 healthy, seronegative adults aged 18-50 in East Africa, South Africa, Thailand, and the United States. The objective was to test several possible vaccine combinations in order to provoke an immune response. But this one was "robust", praised Professor Barouch.
In a separate study, these same vaccines offered protection to two thirds of the 72 macaques to which the researchers then tried to inoculate the virus.
The results of the large-scale test are expected for 2021 or 2022.
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