Promising results of an HIV vaccine



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A Text of Alain Labelle

The present works published in the medical journal The Lancet (in English) showed that this experimental vaccine against HIV-1 was well tolerated and generated good immune responses in 393 healthy adults aged 18 to 50 from Africa, Thailand, and the US

Treatment also produced an anti-HIV immune response in monkeys rhesus.

Further tests are in progress to determine whether the immune response produced is sufficient to prevent HIV infection.

These results represent an important step towards the creation of a vaccine.

Dan Barouch, Harvard Medical School

Did you know?

Currently, 37 million people live with HIV / AIDS on the planet. No less than 1.8 million new cases were diagnosed in 2016.

A virus difficult to define

Despite the many advances in treatment, there is still no cure for HIV. The development of a preventative vaccine could, according to the researchers, lead to its eradication.

This vaccine is one of five experimental concepts of HIV-1 vaccines that have led to efficacy trials. in humans since the onset of the pandemic 35 years ago

Previous HIV vaccines have been tested in specific regions of the world

In this study, researcher Dan Barouch of the Harvard Medical School, and colleagues from several educational institutions around the world, took pieces of different strains of HIV and combined them to trigger immune responses against a wide variety of strains. of HIV

The goal was to define the optimal dosage to proceed to clinical efficacy trials

These results should be interpreted with caution

Dan Barouch, School of Medicine The main obstacles to the creation of a vaccine are the high number of HIV strains and the ability of the virus to mutate rapidly to escape the attacks of the immune system.

did you know?

According to national estimates, approximately 75,500 Canadians were living with HIV by the end of 2014.

Current trials are aimed at improving the performance of the RV1447 trial in Thailand, which showed a modest protection of 31%, a percentage considered too low for the vaccine to be used regularly.

It is important to be cautious and to be clear that there is still much work to be done before an effective vaccine HIV is available

Michael Brady, Terrence Higgins Trust

In the meantime, there is currently a way to avoid the virus, Pre-exposure Prophylaxis (PrEP), which is prescribed to uninfected people, but hautem exposed to HIV. But unlike vaccines, it must be taken regularly to prevent infection.

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