Study Provides Insight into Sun-induced Damage to DNA and Cell Repair
[ad_1] The Rad4 / XPC protein dynamically cooperates with the DNA duplex to "open up" and recognize photoproduct 6-4 (6-4PP), a major DNA-induced lesion induced by sunlight. Here is a new structure that shows how 6-4PP is completely ejected from the DNA double helix by the Rad4 / XPC protein that initiates nucleotide excision repair. … Read more