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A patient with cystic fibrosis developed cancer soon after receiving a lung transplant from a smoker in France according to a study published in the journal Lung Cancer, which warns of the risk transplantation of this type. organs.
The patient was treated since childhood with cystic fibrosis. After the rapid deterioration of their respiratory functions, characteristic of this disease, the doctors decided to carry out a lung transplantation.
"According to the donor database, the transplanted lungs belonged to a 57-year-old woman, I had smoked a pack of cigarettes daily for 30 years ", according to a study conducted by medical oncologists at Montpellier University Hospital (south).
The study notes that tests performed at the time of death The donor's brain did not reveal any abnormalities.
In June 2017, the sick patient was admitted to the thoracic oncology unit of the aforementioned hospital. Two months later, he died of lung cancer and could not be treated with any therapy.
According to the study, the symptoms correspond to those of cancer due to tobacco.
"The short time that has elapsed between lung transplantation and the appearance of the first radiological abnormality suggests that carcinogenesis began the life of the donor" add the authors of the work. A cancer whose growth would have been greatly accelerated by the immunosuppressive treatments received by the patient to avoid rejection of her new lungs.
According to Dr. Jean-Louis Pujol and colleagues, "taking into account latency, for relatively long lung cancer, we suggest that transplant recipients of smoking (or recently quit) donors ) be treated with caution. "
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