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The results of this research, which allow scientists to regenerate partially amputated frog legs, can serve as a model for new cell stimulation therapies and enable advances in the treatment of amputation lesions in the body. 39; man.
Certain species of the world Animals, such as lizards or crabs, are able to regenerate, but this does not occur in the case of the African nail frog, known under the scientific name of Xenopus laevis and examined in this case. study.
This type of water frog is able to regenerate its limbs in the early stages of its life, but loses this ability to adulthood.
The researchers divided the frogs into three groups to perform their experiment and they all sewed the bioreactor. portable just in place of the wound left by the amputation.
Only frogs in any of the groups received progesterone through the biore. during 24 months, the researchers observed a partial regeneration of their unobserved ends in the other two groups.
"A very brief application of the bioreactor and its payload (Michael Levin, one of the authors of the study and biologist at the Allen Discovery Center at Tufts University in Mbadachusetts, United States.
progesterone showed partially regenerated legs, with bone, innervation and vascularization, and could swim once placed in the water as if they had not been amputated.
Progesterone is a bad hormone known for its early functions and development of pregnancy, but it has also been shown that it promotes the repair of nerves, blood vessels and bone tissue.
"We examined progesterone because it seemed It also stimulates the repair and regeneration of the nerves, and modulates the immune response to promote healing and triggers the regrowth of blood vessels and bones, "said the neurologist. Oscar-winner Celia Herrero-Rincón, author of the study.
The next step for researchers is to conduct a similar study in mammals. and try to get more evidence that the drug-device combination may constitute a new model for testing therapeutic badtails to induce the regeneration of non-regenerative species.
Worldwide, millions of people live with a lower, lower, or lower limb. superior, amputated and only in the United States, there are two million.
Source: EFE
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