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The patient was treated since childhood with cystic fibrosis. After the rapid deterioration of their respiratory functions, the doctors decided in November 2015 to perform a lung transplant.
A patient with cystic fibrosis developed a cancer shortly after receiving a lung transplant from a smoker in France, according to a study published in the journal Lung Cancer, which warns of the risk of transplantation of such organs. 19659003] The patient was treated since childhood with cystic fibrosis. After the rapid deterioration of their respiratory functions, characteristic of this disease, the doctors decided to proceed to a lung transplant.
"According to the donor database, the transplanted lungs belonged to a 57-year-old woman who had smoked a pack of cigarettes every day for 30 years," according to a study by medical oncologists the University Hospital of Montpellier (south).
The study indicates that tests performed during brain death of the donor did not reveal abnormalities.
In June 2017, the sick patient was admitted to the thoracic oncology unit of the aforementioned hospital. Two months later, he died of lung cancer without being able to try any treatment.
According to the study, the symptoms correspond to cancer caused by smoking.
"The short time between lung transplantation and the appearance of the first radiological abnormality suggests that carcinogenesis began during the life of the donor," the authors of the study add. A cancer whose growth would have been greatly accelerated by the immunosuppressive treatments received by the patient to avoid rejection of her new lungs.
According to Dr. Jean-Louis Pujol and colleagues, "given the relatively long latent lung cancer latency, we suggest that transplant recipients of smokers (or recently quitters) be treated with caution." [19659009]! function (f, b, e, v, n, t, s)
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