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According to a study published in the journal Science Translational Medicine, the appendix serves as a reservoir for the lfa-synuclein protein badociated with this disease that affects memory. As a result, appendectomy reduces the risk of developing Parkinson's disease.
"Our results indicate that the appendix is an original site for Parkinson's disease and offers a way to devise new treatment strategies that take advantage of the role of the digestive tract in the disease," said Dr. 39, principal author, Viviane Labrie.
"Although reputed to be largely useless, the appendix actually plays an important role in our immune system, in regulating the composition of our organism, intestinal bacteria, and now, as our work shows. , in Parkinson's disease, "explained the scientist.
Reducing the risk of Parkinson's disease became evident only when contained annex and alpha-synuclein were eliminated early stage of life, years before onset of the disease, which suggests that the appendix could participate in its early O.
The elimination of the appendix after the beginning of the pathological process however had no effect on its progression.
The most common. In the general population, people who had an appendectomy were 19% less likely to develop Parkinson's disease, which was amplified in people living in rural areas, with appendectomies resulting in a 25% reduction in the risk of developing the disease. .
The study found that the incidence of this disease is often higher in rural populations, a trend that has been badociated with increased exposure to pesticides.
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