Discover new links on why obesity prevents cancer



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A survey conducted by Trinity College Dublin (Ireland), found new links between obesity and cancer which explains why the immune system fails to fight cells. carcinogenic in case of excess fat.

The study published in the journal Nature Immunology badyzes the causes of because of the failure of immune surveillance systems . ] which are formed by cells called NK (Natural Killer) a type of natural killer cells whose function is to destroy cancer cells.

In addition, scientists have described possible new treatments help NK cells to be reprogrammed at the molecular level to return to action.

The importance of this new study, led by Associate Professor of Immunology Trinity C ollege Lydia Lynch, lies in the knowledge that contributes to the impact of obesity on the patient. immunological action performed by NK cells.

The team led by Lynch, who worked with human cells detecting cancer and implanted them in mice, confirmed that excess fat does not prevent these cells to recognize their tumor counterparts, but prevents them from killing them.

In later research, succeeded in reprogramming NK cells and restoring their effectiveness in the fight against cancer.

Researchers found that more than 1.9 billion adults in the world were overweight and that over one-third of the adult population was obese, resulting in a high number of adults. 39, adverse effects on health.

People with excess weight are more likely to suffer from type 2 diabetes, cardiovascular disease and a wide range of infections in addition to the fact that up to 50% of some cancers are attributed to this diabetes. Pathology.

Lynch said that although the public was increasingly aware of the risks badociated with obesity, it continued to prevail in society.

"It is increasingly urgent to understand the ways in which obesity is the cause of cancer and leads to other diseases and, therefore, to develop new strategies to prevent its progression", said the expert.

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