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Finding an HIV vaccine has been a challenge for scientists. But researchers from various institutions have announced that they have tested an experimental "mosaic" vaccine against HIV, which has caused an immune response between humans and protected monkeys against infection.
The development of this potential vaccine, safe for humans, is now "These results represent an important step" towards the creation of a vaccine, according to the study's director, virologist Dan Barouch , from the Virology Center. Vaccine research at the Beth Israel Deaconess Medical Center (Boston, USA), in addition to Harvard and MIT, in a statement in The Lancet.
However, he warned that there is no guarantee that the next tests are positive. "We have to be careful," he says. For this vaccine with mosaic antigens – designed to cope with the diversity of the virus – scientists have developed a treatment consisting of fragments of different HIV viruses.
Two-thirds of the rhesus monkeys having undergone treatment
The study in humans was conducted among 393 healthy, HIV-negative adults, aged 18 to 50, in Africa. East, South Africa, Thailand and the United States. United Some were given a placebo
The tests showed the safety of the combination of vaccines, which includes different types of HIV virus, with only five participants having adverse effects, such as diarrhea or vertigo
. 72 monkeys that the researchers tried after the virus inoculation.
"True, this is not the definitive vaccine, but it can be a phenomenal breakthrough," said French Jean-Daniel Lelivre, of the Vaccine Research Institute
. According to the World Health Organization (WHO), some 37 million people are living with HIV and 1.8 million people contract the disease each year.
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