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The researchers announced Saturday that they had tested an experimental vaccine against HIV, that elicited an immune response between humans and protected some monkeys from infection a news deemed encouraging .
The potential vaccine, safe for humans, is sufficiently advanced to be tested in 2,600 women in southern Africa who transmit the virus. "These results represent an important step" toward creating a vaccine, the study director said. Virologist Dan Barouch, in a statement in The Lancet magazine
However, he warned that there is no guarantee that the next tests will be positive. "We need to be cautious," he told AFP
The researchers claimed that two-thirds of the rhesus macaques who had been treated were protected by the vaccine in laboratory tests.
The results of tests after Barouch
it is the "fifth concept of vaccine" against HIV tested in 35 years. Another, called RV144, has shown that it protects the human being from HIV up to a certain degree. point In 2009, a study showed that the risk of infection was reduced by 31.2% among 16,000 volunteers in Thailand
The study published Saturday was conducted among 393 adults in good health seronegative, between 18 and 50 years of age in East Africa, South Africa, Thailand and the United States. Some of them received a placebo
Tests showed the safety of the vaccine combination, which included different types of HIV virus, with only five participants having side effects such as diarrhea or dizziness.
These same vaccines protected two-thirds of them. the 72 macaques that the researchers tried after the inoculation of the virus
"We need a vaccine" said François Venter of the University of Witwatersrand (Africa from South). But "we have already known: promising experimental vaccines that do not materialize."
"This is certainly not the definitive vaccine, but it can be a phenomenal breakthrough," says Frenchman Jean-Daniel Lelièvre. Vaccine Research Institute. "At best", these surveys will produce a vaccine that can be administered in "almost ten years".
According to the World Health Organization (WHO), some 37 million people are living with HIV and 1.8 million people contract it each year. Illness has killed about 35 million of the 80 million that it has infected since it was diagnosed in the 1980s.
Despite advances in medicine in prevention and the treatment of the disease (PrEP, antiretrovirals, triterapies), the researchers insist on the measures to be taken not to be infected: protection during bad, use of new syringes, sterilization of medical equipment, etc.
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