Diabetes increases the risk of cancer, especially in women

CITY OF MEXICO (THE UNIVERSAL) .- Diabetes increases the risk of cancer, especially in women as shown by researchers at the George Institute for Global Health at the University of New York South Wales of Sydney (Australia) and the University of Oxford (UK), whose work was published in the journal "Diabetologia." To reach this conclusion, the scientists badyzed 107 published articles and 36 cohorts of patient data,

The statistical badysis took into account diabetes (types 1 and 2 combined) with cancer cases in men and women and, for tumors that can occur in both bades, specific cancer events were badyzed. a. In this way, the researchers found that women with diabetes had a 27% risk of cancer while the percentage among men rose to 19%.

This risk was particularly pronounced in women in the case of kidney cancer (11% more), oral cancer (23% more), stomach (14% more) and leukemia (15%). However, in liver cancer, the risk for women with diabetes was 12% lower than that for men with diabetes.

In this regard, the experts pointed out that hyperglycemia (ie) can have carcinogenic effects by causing damage to DNA, a potentially more pronounced effect in women because, historically, women have been treated less, receive less intensive care and have fewer antidiabetics than men

. and since it has been found that the average duration of impaired glucose tolerance or fasting glucose is greater than 2 years in women, they may be more exposed to untreated hyperinsulinemia (high blood pressure). Insulin) in the pre-diabetic state.

For all these reasons, researchers have emphasized the importance of a gender-specific approach for quantifying the role of diabetes in cancer research, prevention, and treatment. However, they acknowledged that more studies are needed to clarify the mechanisms underlying the differences between the bades in the badociation between diabetes and cancer.