First clinical trials against Parkinson's disease in humans



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Nippon researchers will begin a clinical trial this week to treat Parkinson's disease using induced pluripotency (iPS) cells the first such test to be performed for this disease neurodegenerative. The clinical trial, which will begin next Wednesday, consists of the implantation of healthy nerve cells in the patients' brains to complete the damaged nerve cells as announced in the # Kyoto University on a wheel

The team, led by Professor Jun Takahashi of the University's Center for Research and Application of iPS Cells, received Japanese government approval to begin treatment of seven patients.

already tested in the trial in monkeys and found that none of the animals developed brain tumors that could turn into cancer in the two years that have followed the experiment, as warned some experts

The new treatment would be covered by the health system of the Asian country and aims to serve the growing number of patients with this disease. , about 160,000 people in Japan, according to figures from the Japanese agency Kyodo

Parkinson's disease, for which there is no treatment, reduces the neurons that produce dopamine in the brain and produces tremors in the hands and feet and rigidity in the body.

"I would like this treatment to be available to people as soon as possible" Kosei Hasegawa, president of the Parkinson's Association, said in statements collected by Kyodo .

iPS cells have already been used in Japan to perform pioneering retinal grafts or to manufacture medicaments for the treatment of extremely rare bone diseases of genetic origin

L & # 39; University of Osaka also plans to use this system to create muscle tissue and thus treat heart failure.

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