Understanding the impact of stress in children

ANI |
Last update: 05-Nov-2018 11:26 IST

<! – 8 minutes ago

->
<! –

– Rajat Sharma

->

Washington DC [USA] Nov. 5 (ANI): A recent study was conducted to understand stress targets in children to suggest new intervention strategies.
The results were presented at Neuroscience 2018, the annual meeting of the Society for Neuroscience.
Excessive stress during fetal or early childhood development can have long-term consequences for the brain: increasing the risk of brain disorders and affecting an individual's response to stress in the brain. adulthood, changing the nutrients that a mother can transmit
The new research suggests new approaches to combat the effects of this stress, such as the inhibition of the production of stress hormones or the " resetting "immune cell populations in the brain.
may develop anxiety, depression or addiction later in life two to four times, while stress during pregnancy may increase the risk of developing an autistic spectrum disorder, as well as several other psychiatric diseases.
Scientists are increasingly discovering the mechanisms by which stress in children or the fetus disrupts brain development and leads to these disorders, which could contribute to the discovery of new therapeutic strategies.
The results of the study show that:
-In a murine model of autism spectrum disorder caused by maternal infection during pregnancy, the renewal of fetal brain immune cells alleviates the symptoms of the disease ( Tsuneya Ikezu, abstract 030.09)
-The stress before or during pregnancy can alter the intestinal bacteria in women and mice, which reduce in mice essential nutrients that reach the brain of fetuses (Eldin Jašarevic, abstract 500.14)
-The early stress of life alters the structure of chromatin in a reward region of the brain of mice, thus making them more vulnerable to stress in adulthood (Catherine Pena, abstract 500.01)
– In raccoons, social behavior and amygdala development are induced by stress. resent (Regina Sullivan, abstract 783.14)
– Early life stress accelerates the development of the fear reaction in young mice, but its effect can be prevented by blocking the production of stress hormones (Kevin Bath , abstract 499.01)
"Research demonstrates the long-lasting and profound effects of stress in early development, from bacteria populations in the intestine to the folding of DNA into the nucleus," said Heather Brenhouse, moderator of the Northeastern University press conference. "Understanding the impact of stress on the development of biological systems can lead to new approaches to patient-specific treatment and better outcomes." (ANI)