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The team fed mice of 30 different diets ranging from 8.3% to 80% fat, 10% to 80% carbohydrate, 5% to 30% protein and 5% at 30% sucrose for three months. equivalent to nine years in humans.
They then recorded more than 100,000 measurements of weight and body fat changes measured using a micro-MRI.
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The results showed that only dietary fats were badociated with an increase in energy intake and weight gain. Professor John Speakman, lead author, said, "The result of this huge study was unequivocal. in their diets. "
"Carbohydrates, including up to 30% calories from sugar, had no effect. The combination of sugar and fat did not have more impact than the fat alone.There is no evidence that a low protein content (up to 5%) stimulates ingestion.These effects of dietary fat seemed to come from the fact that single fats in the diet stimulated reward centers in the brain, thereby stimulating greater absorption, "he explains.
Up to now, it has been difficult to establish which part of the diet the weight gain in humans because food consists of a combination of fats, proteins and carbohydrates, and it is difficult to control diets long enough in humans to see which components are the most important.
suggesting an increase in dietary fat, an increase in carbohydrates (especially s sugars), or a reduction in protein can all lead to overeating and obesity.
However, studies on animals similar to humans may help "A clear limitation of this study is that it is based on mice rather than humans," noted Professor Speakman, "However, mice have a lot of similarities with humans in their physiology and metabolism, and we're never going to do studies where human diets are controlled in the same way for such long periods." that it provides is a good clue that the effects of different diets are likely to be in humans. "
Results can be found publi
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