Herpes virus linked to Alzheimer's disease, antivirals can help



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Scientists have found evidence of a link between herpes infection and Alzheimer's disease as well as the potential of antivirals in reducing the risk of neurodegenerative disease.

In the study, when people who suffered from severe herpes infection were treated aggressively with antiviral drugs, the relative risk of dementia was reduced by a factor of 10.

The herpes simplex virus (HSV) infects most humans in youth or later and remains for life in the body in dormant form in the peripheral nervous system.

Different studies have shown the link between herpes and Alzheimer's. A study conducted by Taiwanese epidemiologists, published in February this year, shows that the herpes simplex virus type 1 (HSV1) leads to an increased risk of developing the disease, University researchers said. from Manchester.

In a commentary, reported in the Journal of Alzheimer's Disease on the three articles, the team argued that they provide the strongest evidence yet for a link of Causation Between Herpes and Alzheimer's Disease

"I believe we are the first to understand this devastating disease that primarily affects the elderly.No effective treatments are still available," said Ruth Itzhaki professor of facsity.

"But we believe that these ava antivirals can have an important role to play in the fight against the disease in these patients.

" This also increases the future possibility of preventing the disease by vaccination against the virus in "8,362 subjects aged 50 years or older who were newly diagnosed with severe HSV infection and were compared to 25,086 people without evidence of HSV infection."

] The risk of developing dementia in the VHS group was multiplied by 2.542 .But, compared with those treated with antiviral treatment compared to those who did not receive it, the late incidence of dementia has been increased tenfold in ten years

Despite the relatively short duration and timing of treatment – in most cases, patients severely affected by HSV1 antiviral seemed to prevent long-term damage in the cervix water that results in Alzheimer's, research has shown.

"We have suggested that the virus in the brain is reactivated by certain events such as stress, immunosuppression, and infection / inflammation elsewhere.

" So, we believe that the cycle HSV1 reactivation in the brain eventually causes Alzheimer's disease in at least some patients. "Itzhaki said.

– IANS

rt / ksk

(This story was not edited by Business Standard staff and is generated automatically from a syndicated feed.)

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