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TORONTO: The administration of supplemental oxygen improves the function of blood vessels of the brain in patients with dementia suffering from lung disease, a study concludes.
Research has shown that people with chronic obstructive pulmonary disease (COPD) have a higher risk of dementia. This could be due to lower brain oxygen levels as a result of problems with blood supply from the blood vessels in the brain.
The study, published in Experimental Physiology, has shown that oxygen therapy improves brain oxygen delivery and neurovascular function in patients with obstructive pulmonary disease chronic.
This improvement in cerebral oxygen supply and neurovascular function could provide a physiological link between oxygen therapy and a reduced risk of cerebrovascular diseases such as stroke, mild cognitive impairment and dementia in patients with COPD.
They also tested the link between brain activity and blood flow in the brain. Participants began this test with their eyes closed, opening them to read a standardized text.
The pairing of these ultrasound measurements with a measure of oxygen level in the blood allowed the authors to estimate the amount of oxygen delivered to the brain during the reading test.
The research team found that blood flow and oxygen delivery to the brain were significantly increased during reading. This was because the blood vessels in the brain dilated in response to the increased oxygen demand when the brain was active.
However, this study does not indicate the influence of long-term oxygen therapy on the function of blood vessels in the brain, the researchers note.
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