Radiation therapy reduces the risk of recurrence of breast cancer

Washington DC: According to a recent study, a subgroup of patients with low-risk bad cancer is highly unlikely to return after bad cancer surgery, but may reduce this risk. risk even more with radiotherapy. This 12-year follow-up data from the only prospective randomized trial to compare post-treatment recurrence outcomes for low-risk in situ ductal carcinoma (DCIS) were presented at the 60th Annual Meeting of the American Society for Radiation Oncology (ASTRO).

In this long-term update, patients presenting a "good risk" for DCIS defined by the research team as a cancer discovered only on a mammogram or accidentally during a biopsy of the for another reason continued to present an extremely low recurrence 12 years after bad conservation.

The lowest recurrence rates were observed in patients undergoing whole-bad radiotherapy and those who had also chosen to take tamoxifen, but even those who were no longer receiving treatment as a result of surgery did not have threatening consequences for their lives. ] "I think the most surprising thing was that the recurrence rate in patients randomized to receive radiotherapy was so low.Radiotherapy reduced the number of recurrences by more than 70. Beryl McCormick, principal investigator.

As none of the recurrent tumors in either group appeared to present a risk of death, Dr. McCormick said it was reasonable for patients to determine, in consultation with their physician, if they wished to continue treatment after surgery. [19659003] "All DCIS are not identical, this type of cancer will not have an impact on life expectancy. We have found that radiation significantly reduces the risk of recurrence, but you start with an extremely low recidivism rate, even without radiation. Therefore, both the patient and the doctor need to seriously discuss whether additional treatment should be continued by the patient, "said Dr. McCormick.

DCIS is a cancer of the cells lining the ducts Eligible tumors were 2.5 cm (cm) or less, with margins of three millimeters or less, and low or intermediate nuclear grade.

The badysis included follow-up data at long-term average of 629 patients aged 58, of whom 76% were postmenopausal women, mean tumor size was 0.60 cm (61% less than or equal to 65 cm), 65 percent with margin width 1.0 cm or greater or a completely negative re-excision sample), the highest nuclear tumor grade was 1, found in 44% of patients and grade 2 tumors in the remaining 56%. [1965] "Aucoursdescinqannéessupplémentairesqui Surgical and surgical follow-up was generally increased in the DrCormickCetals increased by 1% in patients who received a follow-up of 3% after surgery

For those who did not receive radiotherapy, the recurrence rate increased by one percentage point per additional year of follow-up, from just under 7%. % to just under 12% after 12 years. Neither age nor the size of the pathological tumor was significant in predicting local recurrence or local invasive recurrence.

end of