Testosterone treatment can bring new hope to cancer patients



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Treatment with testosterone hormone could be effective in combating a condition of body mbad loss in cancer patients and improving the quality of life, say the researchers.

About 20% of cancer-related deaths are attributed to cachexia syndrome, which in cancer patients is often characterized by rapid loss of fat and skeletal muscle.

These results are important because there is currently no therapy targeting this loss of skeletal muscle and without intervention, patients lose their muscle function. and become tired and weakened.

"We were hoping to demonstrate that these patients would not feel well enough to even get out of bed to at least have a basic quality of life that allows them to take care of themselves and receive therapy," said Melinda Sheffield-Moore, professor at the Medical Branch of the University of Texas, United States.

She said the previous nutrition-focused treatment had not been successful in fighting " We already know that testosterone builds skeletal muscle in healthy individuals, so we tried to use it in a population at high risk of muscle loss, so these patients could maintain their strength and performance to be in able to receive standard cancer therapies. Sheffield-Moore said.

For the study, published in the Journal of Cachexia, patients with a type of cancer known as squamous cell carcinoma were treated with standard chemotherapy and / or radiotherapy in addition to seven weeks of treatment, testosterone or placebo.

Total body mbad and lean body mbad increased by 3.2%

Body mbad is important as body mbad decreases 20% or more depending on the type of testosterone Patients also demonstrated improved physical activity

"They felt good enough to get up and take care of some of their basic daily activities, such as cooking, cleaning and bathing, "said Sheffield-Moore.

IANS

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