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London- Stopping the dysfunction of blood vessel cells can reverse the symptoms of small vessel disease (DSV) – the leading cause of dementia and stroke – and prevent Brain injury in older adults,
study, conducted by the University of Edinburgh, found that MV occurs when the cells lining the small blood vessels in the brain become dysfunctional, causing the secretion of a molecule in the brain.
Molecule Stops Production of Protective Layer "This important research helps us understand why small vessel disease occurs, providing a direct link between small blood vessels and changes in the brain that are related to dementia ", said Anna Williams of the MRC Regenerative Medicine Center at the University of Edinburgh in Scotland
" It also shows that these changes can be reversible, paving the way for potential treatments, Williams
In the study, published in the journal Science Translational Medicine, the team used the rat model and found that treating them with drugs that can reverse the changes in blood vessels in the brain badociated with the disease of the small cerebral vessels
"The results highlight a promising direction for the search for treatments that could limit the adverse effects of changes in blood vessels and help keep nerve cells functioning longer, "said Sara Imarisio, head of research at Alzheimer Research in Britain
. Studies are needed to test whether the treatment also works when the disease is firmly established, the researchers said.
Dementia is one of the biggest problems facing society because people are living longer and the population is aging
47 million people with dementia around the world and the number of people affected should double every 20 years, reaching more than 115 million by 2050. (I ANS)
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