Scientists develop antibiotics for drug-resistant bacterial infections in newborns



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  Scientists said the study will reveal more information on mortality, the use of antibiotics and the duration of antimicrobial therapy. Photo: Mint "title =" Scientists said the study will reveal more information on mortality, the use of antibiotics and the duration of antimicrobial therapy. Photo: Mint "clbad =" img-responsive "/> 

<p> Scientists said the study will reveal more information on mortality, antibiotic use and duration of antimicrobial therapy Photo: Mint </p>
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<p><b>  New Delhi: </b> The Medical Research Council (ICMR) has initiated joint research with the Global Antibiotic Research and Development Partnership (GARDP) to develop new antibiotics against drug-resistant bacterial infections in newborns. </p>
<p>  GARDP is a joint WHO initiative The observational study is being conducted at three sites in India, including the Lady Hardinge Medical College of New Delhi, the King Edward Memorial (KEM), Mumbai and the Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) in Puducherry </p>
<p>  The study is also conducted in hospitals and neonatal units at Bangladesh, in Br in China, Greece, Italy, Kenya, South Africa, Thailand, Vietnam and Uganda. da. It focuses on gathering information about babies with clinical sepsis. </p>
<p>  The study will generate an evidence base on the management of neonatal sepsis, which can then be used as a basis for evaluating future interventions in neonates (neonates). Neonatal sepsis is a type of neonatal infection and specifically refers to the presence of a bacterial infection of the blood stream, such as meningitis, pneumonia or gastroenteritis with fever. </p>
<p>  Scientists said the study will reveal more information on mortality, the use of antibiotics and the duration of antimicrobial therapy. Currently few data are available on these settings. Limited research on newborns has resulted in the lack of evidence on the appropriate treatment of serious and drug-resistant infections in this vulnerable population. </p>
<p>  Doctors claim that sepsis, the body's response to infection, can threaten life and poses a particular threat. newborns because their immune system is not fully developed. Increasing rates of bacterial resistance to existing therapies are reported globally, with hospitalized infants and infants at high risk of developing drug-resistant nosocomial infections. </p>
<p>  The susceptibility of newborns to sepsis is further compounded by the difficulty of diagnosing serious bacterial infections, as the symptoms and signs may be nonspecific and difficult to detect, say the doctors. </p>
<p>  "Antimicrobial resistance is one of the greatest threats to global health, food security and development today." It is a public health problem major and rapidly growing worldwide, with estimates of up to 700,000 deaths per year.AMR threatens to undermine the progress we have made as a country to control infectious diseases such as Malaria and Tuberculosis, "said Anupriya Patel, Minister of State for Health and Family Welfare </p>
<p>a critical priority, and called for effective measures to address them. and Family Welfare identified AMR as one of the 10 priorities of the ministry's collaborative work with WHO, "she added. </p>
<p>  The study aims to guide the development of new treatments and reverse the overall increase in newborn deaths. The observational study, led by GARDP, received $ 2 million in funding from the Bill and Melinda Gates Foundation. </p>
<p>  While significant progress has been made in recent years to improve the health of children around the world, including a 50% reduction in infant mortality since 1990, the number of preventable deaths among newborns remains unacceptable. Neonatal deaths now account for 44% of all deaths among children under five. </p>
<div clbad= First published: Thu, Jul 05 2018. 10 43 PM IST
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