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Cancer affects everyone. The total number of large companies is no exception. Glioma is the disease that has constantly hurt President Koo Bon-moo, Chairman of LG Group. The average survival time is less than 1 year.
Recently, national SMEs have boldly challenged the development of new drugs to treat brain cancer with glioblastoma. It is Komi-Pam who researches and develops mainly veterinary drugs. The know-how in the development of veterinary drugs is the basis of the study of human drugs. Global pharmaceutical companies such as Pfizer and Bayer are also researching and developing veterinary drugs such as Comifam. Dr. Song Bong-kyu (pictured) of CombiPharma, a research and development company of a cancer drug telomere (product name: Cominox), a new mechanism for directly targeting the telomeres of cancer cells, It is responsible for the production of clinical trial drugs for the production of comminox, quality control and progression of clinical trials.
Song suggested the possibility of differentiating between anticancer drugs. "We hope that if we directly target the telomere of cancer cells like Kominox, we will be able to treat cancer more fundamentally," he said. Telomeres are a kind of "cell timer" involved in cell life. When the telomere is destroyed, normal cells turn into cancer cells and proliferate to infinity. Targeted anti-cancer drugs are resistant to treatment after a long time and their effectiveness has been limited, depending on the individual. Telomeric anticancer drugs, on the other hand, have no such limitations. This is because of the mechanism of action of telomeric anticancer drugs. "All cancer cells are damaged by telomere, and when they are treated with anticancer drugs like coxinox, cancer cells, as well as cancer recurrence and metastasis, can effectively eliminate cancer stem cells, that play a crucial role in the proliferation of cancer. "
The destructive effect of kominox cancer cells is encouraging. Basic research using nanotechnology has confirmed the widespread effect of cancer destruction. Song said, "More than 180 of the 200 cancer cells tested have been killed." This means that it can be applied to most cancer treatments.
Clinical trials are underway to confirm the effectiveness of cancer treatment. The first clinical trial is a glioma. Dr. Song said, "Dr. Charles Teo, who enjoys a good reputation in the field of glioblastoma treatment, has considered the possibility of a treatment by pathox and suggested the clinic first. , brain cancer is difficult among cancers The brain barrier (BBB), a defense system that prevents harmful substances from entering brain tissue, blocks cancer drugs Currently, the rate of pbadage of temozolomide (TMZ) a standard treatment of glioblastoma cell tumors is between 20 and 30%.
In addition, Cominox has a penetration rate of 98% of BBB. Song Jung-moo was convinced that "Cominox will be a new star drug that will go beyond immunotherapy with a new mechanism different from existing anticancer drugs".
Kwon, Sunmyum reporter [email protected]
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