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A large team of scientists (from the Chan School of Public Health, the National Cancer Institute of the United States and more than 20 other medical societies and centers) found that concentrations high levels of vitamin D were badociated with a lower risk of colorectal cancer. .
This study supports previous evidence that has been considered inconclusive about the relationship of vitamin D to this type of cancer.
Optimal vitamin D concentrations for colon and rectal cancer may be higher than those recommended by the National Academy of Medicine, which is based solely on bone health.
(This study appeared online in the Journal of the National Cancer Institute).
Vitamin D, known for its role in the maintenance of bone health, is believed to reduce the risk of colorectal cancer by many pathways related to cell regulation and growth.
Previous studies have shown unequal results as to whether high concentrations of 25-hydroxyvitamin D-rolling lead to a reduction in the incidence of colorectal cancer or not.
Few randomized clinical trials on vitamin supplements and rectal colorectal cancer showed no effect, but study size, duration of supplements, and response may have contributed to his false results. "To address inconsistencies in previous vitamin D studies and to verify vitamin-related data binding, we badyzed data collected from 17 groups prior to the diagnosis of colorectal cancer," said Stephanie Smith, an epidemiologist at the University of Toronto. 39, Harvard University. Expected, and the use of standards in all studies ".
The study involved the badysis of more than 5700 cases of rectal colon cancer and 7,100 cases as a control group in the United States, Asia, and Europe.
A single laboratory trial has been widely accepted for new measurements of vitamin D. "In the past, fundamental differences in vitamin D parameters have made it difficult to integrate vitamin D data from from different studies, "said Regina Regler, PhD, epidemiologist at the National Cancer Institute. The calibration of systemic risk detection is systematically around vitamin D levels.
The study showed that vitamin concentrations adequate for bone health were badociated with a rate of 30%. infection was 30% higher and the highest concentrations were badociated with a risk of infection of less than 22%. The level of badociation between higher vitamin levels and a lower risk of infection in women was higher than that of men!
Colorectal cancer is the third most common type of cancer, and the third causes deaths among both men and women in the United States with approximately 140,250 new cases and 50,630 deaths expected in 2018.
Dr. Margie Macaulog, Epidemiology at the American Cancer Society and one of the participants in the study: "Currently, the health agency does not recommend vitamin D for prevention colorectal cancers. "
"This study has provided new information that agencies can use when examining evidence to guide vitamin D, and suggests that recommended bone health concentrations may be less than ideal for preventing this type of cancer, "he said.
Vitamin D can be obtained in the diet, supplements and exposure to sunlight, but experts recommend vitamin D as part of a diet because too much of UV exposure is one of the causes of cancer. So, skin, you should be careful.
- Translation: Mohammad Ghazi.
- Verification: Visions of Drakhbani.
- Editing: Suha Yazji.
- Source
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