A new AIDS vaccine shows an extraordinary immune response to humans



[ad_1]

An experimental vaccine, developed by scientists more than 40 years ago, showed an immune response to humans and was successful in protecting monkeys from infection, according to a study published in the Lancet medical journal. The vaccine will be tested in the next phase of the trial, after it has been proven safe in humans and will be tested on 2,600 women in southern Africa to determine if it will prevent AIDS.

However, the research team and the experts from abroad warn that despite the encouraging results so far, this does not guarantee the success of a drug in the next experimental phase called "HTNV705" or "Imbukudu", meaning the rock in Zulu.

Dan Barroch, a study supervisor and professor at Harvard University, told AFP: "Although" the fact that the vaccine has managed to protect two-thirds of the monkeys in a lab experiment does not mean that he's going to protect humans, so we have to wait for results … study before we know what, "he said. AIDS. "

The results of Imbukudu should be published in 2021 or 2022.

" This is the fifth vaccine which will test its efficacy in humans over the 35 years of life. history of the disease worldwide. "

A vaccine, called RV144, has shown a form of disease prevention. The RAV 144 was announced in 2009 to reduce the risk of HIV infection by 31.2% among 16,000 Thai volunteers, but was deemed insufficient to be clbadified as antiretroviral.

Baroch and his team tested the vaccine candidate on 393 healthy adults without AIDS and at a distance. 18 to 50 years in East Africa, South Africa, Thailand and the United States.

Volunteers were randomly badigned to a group of vaccines or a placebo and four doses at 48 weeks.

These combinations combine different types of (19659002) vaccine. "The vaccine has produced the most potent immune responses (at high levels) in humans," he said.

Tests also showed that the vaccine [5] In a separate study, the drug was found to be a complete prevention of AIDS in two-thirds of the 72 monkey monkeys that had received six doses. AIDS.

He urged Franco Venter, from Ytwatersrand University for Health

He told AFP: "We were at this stage before, when we developed vaccines promising candidates but who have not developed. "

He continued, "This" The drug is new in many ways, so it's an exciting vaccine, but we still have a long way to go. "

Jean Daniel Lilliver of the Vaccine Research Institute in France said that the vaccine was probably not "final" outstanding progress. "

According to figures from the World Health Organization, people living with AIDS are estimated at 37 million According to the BBC, nearly 1.8 million people die of the disease and about one million die each year.

Estimates of 80 million people have been diagnosed with HIV since the diagnosis of the disease for the first time in the early 1980s and about 35% have died in the world so far. No drug has proven effective because the HIV virus grows easily and can only hide in cells and escape the immune system to reappear and spread years later.

AIDS patients rely on therapies to inhibit the The male is the first way in the prevention of eczema The infection for badually or blood communicate, but often prefer to use the treatment of the Inhibition of the virus as a means of prevention.

comes the results of the latest study in the run-up to the International AIDS Conference to be held in Amsterdam from July 23 to July 27 this month.

[ad_2]
Source link