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Is there a day when the word infertility disappears from the dictionary? "I do not think we are going to get rid of infertility, but it is clear that great strides have been made in recent years in treatment and gave patients a lot of hope," said the Dr. Paul Serhal. "
Dr. Paul Sarhal, one of the most famous infertility specialists in Britain, comes from the Lebanese city of Jezzine and publishes major world media titles in December of the year. 39, last year 2009. It has been successful during artificial insemination in the eradication of the genetic gene Breast Cancer of the egg before fertilization and implantation in the uterus of one. This operation prevented cancer from appearing in a family whose women were predominantly bad cancer.The completion of Sarhal has helped in the detection of eggs stored in women and therefore the chances of Remaining pregnancy, especially with the increasing number of women born after the age of 35.
Through her extensive experience in infertility in women and men Serhal is one of the leading global specialists in new technologies, tell es that pre-implantation genetic diagnosis and the development of fertility treatments. Sarhal left Lebanon at the age of 12 and arrived in the United Kingdom where he is still today stable. He is a certified consultant in reproductive medicine and a member of the Royal College of Obstetricians and Gynecologists of the Kingdom. In 1990, he was appointed Honorary Consultant in Reproductive Medicine and also became a Lecturer at the University College of London
– Your name in the world of medicine and medicine. ;obstetrics.
It is impossible to build a career on the basis of a single accomplishment, but it is linked to a permanent commitment to medicine, science and humanity that pushes you to seek science, perseverance and diligence at work.
– What distinguishes Dr. Serhal in the field of infertility and obstetrics?
After years of experience in reproduction, we have been able to develop several techniques used today to help the infertile patient, be it male or female . We have done a lot of work in collaboration with University College London Hospital, regarding the structure and development of the diagnostic technology that precedes the gene implantation. This technique is used to diagnose a specific genetic mutation and any abnormal gene in the patient when it belongs to a family with a history of bad cancer or another type of cancer or another hereditary illness. Therefore, the idea is to fertilize the oocyte in vitro and form a fetus and test any abnormal gene.
For this, we realized the first case of retinal cancer in the world. At that time, the technique of testing or diagnosing the fertilized egg was certainly unknown, but nowadays it is a common procedure. I am happy to see that this technique has become a mechanism and we do not need large laboratories to perform the genetic test. It is wonderful to see the evolution of the initial phase, which is commonly performed in many centers by the central laboratories.
| 20% of bad cancers have genetic causes (1965). In 2009, you were able to eradicate the gene gene Chest. The genetic mutation (BRCA1) or BRCA2 may carry the risk of bad cancer and ovarian cancer. If a woman carries this mutation, her bad cancer will increase by 90% while ovarian cancer will increase by 80%. In this case, the bads must be removed and restored. It is also better for women to remove the ovaries after having the children you want. The probability of transferring the abnormal gene to boys is 50%. What we did was that we took eggs from women carrying the genetic mutation and put the fertilized eggs in the lab and tested them, because half of those eggs carry the genetic mutation and the other half is normal. We transferred the natural fertilized eggs without the genetic mutation in the uterus, so the fetus is not affected by the genetic mutation and we are prevented from forming its cancer.
It is important to note that I am talking about a type of bad cancer. But the rest has nothing to do with genes but with the effects of the environment. Today, this process is known and it is natural that cancer of the intestine, bad cancer or any other type of cancer in the genes can be eliminated in the lives of future generations. And that's where the strength of this technique lies. – Is it still impossible for women to bear sometimes? Certainly … When women reach menopause and have lost all their eggs, it is not possible to do a lot of interventions for these women. The same goes for those born without bread. It is true that it is rare, but it happens that women are born with ovaries but no uterus. They can be born after a transplant of the uterus. Matrix transplantation is a major challenge because it involves the administration of blood vessels to the uterus. I suspect that with robotic surgery this process will become a lot easier. It has been realized in recent years for 40 cases worldwide, first in Sweden. Until now, 11 children are born through this process, and very soon it will be conducted for the first time in Britain. It is possible that this process will fail as any other process, and it depends on the skill of the surgeon. But over time, robotic surgery will improve the result – Numerous studies point to the increase in infertility in men worldwide, and in the Arab world in particular. What are the causes? Male infertility is generally on the rise, and I do not think there is a geographical difference, but it is a problem that occurs all over the world. There is clearly a decrease in the quantity and quality of sperm, and it is difficult to identify a cause. There are many theories related to this, including pollution or exposure to plastic, but he has not insisted on making sure that it is the direct cause that affects the sperm. Certainly, general problems such as heat or some treatments can affect the quality and quantity. – What is the technique for implantation of frozen ovarian tissue? The idea of freezing ovarian tissue is mainly for girls who have not yet been incubated, because when the girl reaches puberty Stem cells and non-tissue cells with a rate of high success. If a woman wants to maintain her fertility because she has cancer or a history of early ovarian failure in her mother's family, then we are in favor of egg freezing. There is a blood test today to measure women's egg reserves, and I suggest it to any woman over the age of 30 because the eggs are reduced. I think that the process of freezing eggs is now normal in Europe, especially since many women continue their studies and start working, over time and end up at the age of thirty five years. If they do not have a partner, the possibility of freezing the eggs remains good, knowing that this certainly does not guarantee reproduction. The way we collect eggs remains the most important. We are at the center, collected by the abdomen, because women who do not have a partner worry about their virginity. Fertility begins to decline after 5 years – Do women delay pregnancy beyond 30 years? In women, we support motherhood before reaching this age. Naturally, the fertility level is good up to the age of 35, when the decline begins. Some women sometimes think that they can use IVF without realizing that the egg itself is naturally vaccinated or by technique. Therefore, if we examine the success rates of this technology, we find that it begins to decline at the age of thirty-five. Today, the technology we have developed for these women helps us. The genetic diagnosis of chromosomal abnormalities in the fertilized egg plays an important role in selecting the best ones. This will eliminate the relationship between age and success rate. At the age of 35 and over, the rate of eggs with abnormal pigmentation increases. If we take an egg, we see that there is a small structure called the spindle, which carries all its pigments. The idea is that when we have fertilized eggs in the laboratory, we avoid choosing those that do not have the right number of chromosomes, that is, we try not to choose several eggs that fail. We can transfer an abnormal gene to our children by 50% (Ahmad Al-Daoudi) |
– When is IVF used?
The couple must try to have a child for a year before consulting a doctor because about 80 About one percent of women are detained after almost a year of testing. We are not like rabbits, and we are not species with high fertility. A year later, the couple should use basic tests, such as sperm and oocyte testing, and make sure the tubes are not blocked.
– What problems do men have and how to make normal pregnancy impossible?
Half of our patients have a low sperm count and some do not have spermatozoa. With these, we go to surgery. After administering hormonal treatment for a few months, these sperm are surgically removed from the testes. There are two cases that require this type of treatment, either obstruction or birth with a deficiency of spermatozoa.
– Beyond Infertility, What Is Your Relationship With Lebanon And Great Britain 19459007
Great for me. Here is a different culture, different values and different expectations, and I think the two cultures complement each other. It is wrong to say that this culture is better than the other, both have strengths and weaknesses. While my country's culture has affected me, I have experienced a very strange culture in the UK, to which I have been entrusted with a great inner strength and courage to continue to progress and to overcome the barriers.
– It is said that the doctor does not have the time. Of course, medicine is important, so you do not close your place and do not go home. To think about this is permanent, there are difficult cases that sympathize with patients and live with them their experience. It's like a life commitment even if you are exhausted physically and psychologically. So, you should get used to this model that becomes a part of you. If I was not a doctor, I would sail around the world … I love to sail.
