Scientific breakthrough can protect thousands of "silent killers"



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A group of scientists made a scientific breakthrough that illuminates the causes of sepsis

Thousands of people become "silent killers" when an infection, such as sepsis, causes a violent immune response in which the body attacks the cells of its organs. Current septic screening tests take days, sometimes longer. But the new research paves the way for a much faster method of diagnosing the patient, which greatly increases the chances of survival.

Tests on rats and humans revealed two molecules produced by immune cells during an infection for a long time,

Scientists at Columbia University discovered that high levels of microRNAs, which are small parts of the genetic code, could indicate the need for urgent treatment.

High levels of microRNA, miR-221 and miR-222 indicated immune system in mice with sepsis. The researchers also studied microRNAs from 30 patients admitted to the hospital because of a blood infection.

It was observed that people with signs of organic insufficiency, when sepsis was not treated, had higher rates of miR-221 and miR-222 [19659008] Researchers believe A microRNA test can help diagnose infected patients, allowing doctors to start administering antibiotics and fluids to control the infection faster before an organ fails.

Infections kill 44,000 people in Britain and 250,000 in the United States per year, however, it can be cured very early by using the sow

In case it is not treated immediately it can lead to tissue damage and failure of the main organs of the body. Even if the patient survives, he may suffer brain damage or limb loss.

The diagnosis currently rests on the evaluation of clinical signs, including high frequencies, abnormal heartbeat and respiratory rates.

To confirm the diagnosis, one must send a blood sample to the laboratory, where it is tested and exposed to a number of proteins that would be affected by the infection. The results can take up to 3 days

The new results published in the journal Nature offer the hope of a much faster test.

[Russia]

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