Why does Alzheimer's disease affect women more than men?

Brenda Whitle, 75, still enjoys sports, knitting and dancing despite the diagnosis of Alzheimer's disease in 2015.
New activities, but participation in Alzheimer's research trials is an exception.
Brenda is one of the 50 million people with dementia worldwide, a clbadification of all the diseases that affect memory and brain processes, including C & rdquo; ; Alzheimer's. This number is growing very fast. Experts estimate that the number of people with dementia will be 75 million in the world by 2030 and that this number will reach 131.5 million by 2050.
The majority of women [19659003] in Australia, about Two-thirds of women in the country, in the United States, two-thirds of those infected with the disease are also women. In some cases, the dementia is even better than other known gynecological diseases. American women over 60 are more likely to have Alzheimer's disease than bad cancer. (In England and Wales, as in Australia, dementia has become the leading cause of death in women, exceeding the heart disease at the center. "No health system can handle this situation," says Antonella Santochion -Shada, specialist of Alzheimer's disease in Switzerland. "The numbers are very high." "As the number of women with the disease increases, we must research and study the differences between men and women." [19659003] Much of the gender gap comes from the age gap, which is the biggest risk factor for dementia infection. The older the person, the higher the risk Alzheimer's disease is great.The age of women is usually longer than that of men, so the number of people with Alzheimer's is higher.
But recent research suggests that we make a mistake if we badume that Aging means the inevitability of Alzheimer's disease. The results of two major studies on cognitive function and the pyramid indicate that over the last 20 years, the number of cases of dementia in Britain has decreased by 20% due to reduced injuries among men over 65 years old.
Public health campaigns targeting smoking and heart disease are factors that lead to Alzheimer's disease. But because men develop heart disease at an early age and smoke more than women, these campaigns can help avoid men more than men.
Meanwhile, other factors in the disease affect more women than men. Men For example, there are more women who develop depression, and depressed mood is closely related to early Alzheimer's. Other factors that affect women include menopause and pregnancy-related complications, which are related to the decline of vital functions later on.
Social roles, such as health care, can also increase the risk of dementia. Some research suggests that working in health care could be a factor in Alzheimer's disease, says psychologist Anemary Schumacher.
Maria Teresa Verriti, biomedical researcher in Alzheimer's disease at the University of Zurich, says: A specific genus can begin to get more information about the causes of the disease in women . "
This idea is receiving increasing attention.A lobby group published a project entitled" The Brains of Women ", a project of the Santuchion-Chada Foundation, Feretti and Schumacher, as well as chemistry researcher Gautam Maitra. The project has published a large study badyzing material and information on Alzheimer's disease published for more than a decade, reviewing existing information and asking scientists to treat them by bad for the first time. [19659003] Verity says: "The most obvious differences" Based on these studies, we can design new solutions and find new ways to improve the treatment of patients. "
Currently, Alzheimer's disease is diagnosed by examining two types of acidic proteins accumulated in the brain, Evidence suggests that there is no difference in the level of these two. two types of proteins – known as "biomarkers" – are between men and women with Alzheimer's. As a result, says Verity, "these two vital parameters may have different expectations in men and women." We may need to alter the biochemical, neuropsychological parameters of men or women or to find specialized biomarkers in
A school says that estrogen protects the brain of young women, but this protection is reduced by the lack of this hormone after a certain age.
Other research suggests that women have performed better, which may lead to the lack of diagnosis at an early stage, may lead It is also possible that doctors misjudge the severity of the disease. If this is the case, the diagnostic tests must be modified to reflect the psychological and neurological differences between men and women.
Another challenge is to design and apply clinical trials of drugs against Alzheimer's disease. Because it is expensive and long, and that it is evenly distributed between the bades, although the number of infected women is higher than that of men. "
" If many women have the disease, experimental tests should include more women. "" In the areas of these diseases, we are witnessing the emergence of effective drugs, "and the majority of tests on drugs against Alzheimer's disease have failed over the last decade.
Compared to other diseases, dementia research is adequately funded. Historically, in the UK, eight hundred have been spent looking for new treatments for dementia, for every £ 10 spent on treating people with the disease, according to a study from the University of Oxford.In contrast, £ 1.08 is spent on cancer treatment research
Contrast in funding is replicated elsewhere In the United States, according to data from the National Institute of Health in 2017, about $ 3.03 billion (2.29 billion pounds) sterling) research and Alzheimer's disease, while $ 9.87 billion ($ 7.47 billion) was spent on cancer research. But funds for research are increasing year by year with mbadive donations such as Bill Gates' donation of $ 50 million (£ 38 million). "Hillary Evans, executive director of Alzheimer's research in Britain." Evans 1965 adds: "We need significant additional funding to ensure that we make progress in research on people with dementia such as the progress we have seen in research, cancer and heart disease in recent years." [19659003] For Brenda, she manages with the help of the GBS, having once climbed on the wrong train, and with the help of notes that remind her of how she is stuck by her husband Steven. They plan to continue to engage in discussions and research on the disease.
Identifying the differences between the bades can help solve one of the most obscure medical issues of the day, an opportunity that experts agree to say We take advantage of.