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Use of antibiotics for two months or more may be related to an increased risk of cardiovascular disease in a woman.
The discovery, published in the European Heart Journal, applied to women who used these drugs at the age of 40.
The researchers used data on 36,429 women with no cardiovascular disease at the start of the study who participated in a continuing long-term health study. As of 2004, women reported using antibiotics.
During the seven years of follow-up, 1,056 cases of cardiovascular disease were reported. Compared with women who have never used it, women who used antibiotics for at least two months or more between the ages of 40 and 50 had an increased risk of cardiovascular disease of 28%, and women over 60 who used them for a long time had an increased risk of 32%.
The study controlled family history of heart attack, body mass index, hypertension, the use of other drugs and other factors .
"It is difficult to distinguish the effect of the antibiotic on cardiovascular disease from the effect of the disease for which it was taken, and this is a potential limitation of the study," said lead author , Lu Qi, currently professor of epidemiology at Tulane University. "But it is unlikely that we see the effect of the disease in place of the antibiotic because we are seeing the effects of many diseases using antibiotics."
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