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"Test.Treat.Hepatitis." Is the theme of this year's World Hepatitis Day.The era of direct-acting antivirals has seen a significant increase in the number of patients with HIV / AIDS. The following reports include data on the treatment of HCV in the "microenvironment" of the prison, further research having invalidated the link between ADA therapy and the increased risk of hepatocellular carcinoma. and a report on a new HCV "genotype 8" discovered in four patients.
Treatment of HCV in "microenvironment" in prisons reduces transmission
More and more evidence supports overall benefits and outcomes cost-effective screening and treatment of hepatitis C in the "microenvironment" of the prison, according to a review of recent studies.
"The microenvironment of the prison is considered promising to intervene in the management of blood-borne diseases since this population has a high prevalence of the disease, generally engages in high-risk behaviors and could easily be accessed by suppliers for testing and treatment " Joseph S. Redman, MD, PhD, and Richard K. Sterling, MD, MSc, FACG, of Virginia Commonwealth University, wrote in their review. Read More
Research continues to invalidate the link between DAA treatment, liver cancer
Results from a recent study confirmed the increase in hepatocellular carcinoma rates in treated patients by direct-acting antivirals compared with interferon correlated with patient characteristics such as age and liver function rather than treatment. Long-term follow-up, there have recently been several alarming reports suggesting "exceptionally high" rates of CHC incidence under and after DAA regimens in cirrhotic patients. Pierre Nahon MD, Jean Verdier Hospital in France, and his colleagues wrote. "However, this double increase in risk is modest, time-limited, and can at least partially be explained by confounding factors related to the specific profile of patients with higher risk factors for liver cancer development." . " Read more
New surfaces of 'genotype 8' in four patients infected with HCV
The researchers identified four patients with a new genotype of hepatitis C, according to a study published in The Journal of Infectious Diseases
Despite the genetic distinction of previously identified genotypes of HCV genotypes 1-7, all four patients achieved a sustained virological response with direct-acting antivirals. Read more
Universal screening of HCV in adults is cost-effective and decreasing prevalence
The results of a recent study in France have shown that universal screening is the most effective and cost-effective strategy when treatment was initiated, regardless of the patient's fibrosis stage
"In Europe, recommendations for HCV screening target only those at high risk of infection," Sylvie Deuffic- Burban MD, from the University of Lille in France, and his colleagues wrote. "From an individual point of view and especially from a societal point of view of the 39, eradication of HCV, [universal screening] should be implemented. However, by recommending such a strategy, prompt initiation of treatment after diagnosis is required. "Read more
Alcohol consumption disorder in HCV increases depression, inflammatory response
According to a recently published study, hepatitis C associated with a comorbid disorder associated with a increased depression and anxiety, dysregulated cytokine expression, and impaired blood-brain barrier
that contributes to its adverse effects [central nervous system] and neuropsychiatrics, " Jennifer M. Loftis, PhD, of the Portland VA Health System in Oregon, and his colleagues wrote. "The purpose of this study was to investigate how comorbid [alcohol use disorder (AUD)] contributes to abnormalities in mediators of inflammation and psychiatric disorders in veterans with HCV." Read more
Indications of a liver transplant change, survival is better in the DAA era
The number of hepatic transplants due to decompensated cirrhosis related to hepatitis C and hepatocellular carcinoma has decreased rapidly over the last 3 years while post-transplant survival has improved, according to data from the European Registry of Liver Transplants
. the first time large-scale use of direct-acting antiviral drugs significantly improving the survival of the HCV recipient. Luca Saverio Belli, MD, of the Niguarda Hospital of Milan, Italy and colleagues wrote. "This trend is expected to continue provided that current policies to eradicate HCV infection in the population are maintained." Read more
"Test.Treat.Hepatitis." Is the theme of this year's World Hepatitis Day.The era of direct-acting antivirals has seen a significant increase in the number of patients The following reports include data on the treatment of HCV in the "microenvironment" of the prison, further research having invalidated the link between ADA therapy and increased risk. of hepatocellular carcinoma and a report on a new HCV "genotype 8" discovered in four patients
Treatment of HCV in "microenvironment" in prisons reduces transmission
More and more evidence supports overall benefits and the cost-effective results of screening and treatment for hepatitis C in the prison's "microenvironment," according to a review of recent studies.
"The prison microenvironment is considered as promising to intervene in the management of blood-borne diseases since this population has a high prevalence of the disease, generally engages in high-risk behaviors and could easily be accessed by providers for testing and treatment " Joseph S. Redman, MD, PhD, and Richard K. Sterling, MD, MSc, FACG, of Virginia Commonwealth University, wrote in their review. Read More
Research continues to invalidate the link between DAA treatment, liver cancer
Results from a recent study confirmed the increase in hepatocellular carcinoma rates in treated patients by direct-acting antivirals compared with interferon correlated with patient characteristics such as age and liver function rather than treatment. Long-term follow-up, there have recently been several alarming reports suggesting "exceptionally high" rates of CHC incidence under and after DAA regimens in cirrhotic patients. Pierre Nahon MD, Jean Verdier Hospital in France, and his colleagues wrote. "However, this double increase in risk is modest, time-limited, and can at least partially be explained by confounding factors related to the specific profile of patients with higher risk factors for liver cancer development." . " Read more
New surfaces of 'genotype 8' in four patients infected with HCV
The researchers identified four patients with a new genotype of hepatitis C, according to a study published in The Journal of Infectious Diseases
Despite the genetic distinction of previously identified genotypes of HCV genotypes 1-7, all four patients achieved a sustained virological response with direct-acting antivirals. Read more
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Universal HCV screening in adults is cost-effective and decreasing prevalence
The results of a recent study in France have shown that universal screening is the most effective strategy effective and cost-effective when treatment was initiated, regardless of the patient's fibrosis stage
"In Europe, recommendations for HCV testing target only those at high risk of infection," Sylvie Deuffic-Burban MD, of the University of Lille in France, and his colleagues wrote. "From an individual point of view and especially from a point of view societal view of HCV eradication, [universal screening] should be implemented. However, by recommending such a strategy, prompt initiation of treatment after diagnosis is required. "Read more
Alcohol consumption disorder in HCV increases depression, inflammatory response
According to a recently published study, hepatitis C associated with a comorbid disorder associated with a increased depression and anxiety, dysregulated cytokine expression, and impaired blood-brain barrier
that contributes to its adverse effects [central nervous system] and neuropsychiatrics, " Jennifer M. Loftis, PhD, of the Portland VA Health System in Oregon, and his colleagues wrote. "The purpose of this study was to investigate how comorbid [alcohol use disorder (AUD)] contributes to abnormalities in mediators of inflammation and psychiatric disorders in veterans with HCV." Read more
Indications of a liver transplant change, survival is better in the DAA era
The number of hepatic transplants due to decompensated cirrhosis related to hepatitis C and hepatocellular carcinoma has decreased rapidly over the last 3 years while post-transplant survival has improved, according to data from the European Registry of Liver Transplants
. the first time large-scale use of direct-acting antiviral drugs significantly improving the survival of the HCV recipient. Luca Saverio Belli, MD, of the Niguarda Hospital of Milan, Italy and colleagues wrote. "This trend is expected to continue provided that current policies to eradicate HCV infection in the population are maintained." Read more
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