Motor neuron disease damage could be REVERSE using existing drugs



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Treatment

There is no cure for MND and the disease is fatal, but the disease progresses at different rates in patients.

People with MND are expected to live two to five years after symptoms first appear, although 10% of people with MND will live at least 10 years.

The story

The NHS describes motor neuron disease (MND) as: “A rare disease that affects the brain and nerves. This causes weakness which gets worse over time.

Weakness is caused by deterioration of motor neurons, upper motor neurons that travel from the brain to the spinal cord, and lower motor neurons that spread to the face, throat and limbs.

It was first discovered in 1865 by a French neurologist, Jean-Martin Charcot, hence Charcot’s disease, sometimes called MND.

In the UK, amyotrophic lateral sclerosis (ALS) is called motor neuron disease, while in the United States, ALS is called a specific subset of MND, which is defined as a group of neurological disorders.

However, according to Oxford University Hospitals: “Almost 90 percent of patients with MND have the mixed form of the disease ALS, so the terms MND and SLA are commonly used to mean the same thing.

Symptoms

Weakness in the ankle or leg, which may manifest as tripping or difficulty climbing stairs, and weakness in the ability to grasp things.

Speech disturbances are an early symptom and can then worsen to include difficulty swallowing food.

Muscle cramps or muscle contractions are also a symptom, as is weight loss due to the weight loss of the muscles of the legs and arms over time.

Diagnostic

MND is difficult to diagnose in its early stages because several conditions can cause similar symptoms. There is also no single test used to determine its presence.

However, the disease is usually diagnosed by an exclusion process, in which diseases that manifest symptoms similar to ALS are excluded.

The causes

The NHS says MND is a “rare disease” that primarily affects older people. However, he cautions that it can affect adults of any age.

The NHS says that, as of now, “it is not yet known why” the disease occurs. The ALS Association asserts that MND occurs worldwide “without racial, ethnic or socio-economic boundaries and can affect anyone”.

He says veterans are twice as likely to develop ALS, and men are 20% more likely to get it.

Lou Gehrig was one of the stars of baseball playing for the Yankees between 1923 and 1939. Known as “The Iron Horse,” he played 2,130 consecutive games before ALS forced him to retire. .  The record was broken by Cal Ripken Jr. in 1995

Lou Gehrig was one of the stars of baseball playing for the Yankees between 1923 and 1939. Known as “The Iron Horse,” he played 2,130 consecutive games before ALS forced him to retire. . The record was broken by Cal Ripken Jr. in 1995

Lou Gehrig’s disease

Besides being known as ALS and Charcot’s disease, MND is often referred to as Lou Gehrig’s disease.

Lou Gehrig was an extremely popular baseball player, who played for the New York Yankees between 1923 and 1939.

He was famous for his strength and was nicknamed “the iron horse”.

His strength, popularity and fame transcended the sport of baseball and the condition adopted the athlete’s name.

He died two years after his diagnosis.

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