[ad_1]
Fourteen subjects were locked up for three consecutive days in special breathing chambers of the University of Maastricht. We could not have contact with the outside world, the light from outside was stopped and there was no sense of time – only Netflix was available. Food and drinks were served to the subjects tested via an airlock. After the first "normal" night, the day and night rhythm of the subjects was canceled by letting them sleep a few hours after lunch. In the evening, people woke up for breakfast, followed by another full day. In the morning, they had dinner. This reversal of the day and night rhythm was then repeated again, after which various measurements took place. Professor Patrick Schrauwen, head of research, explains: "Thanks to this unique configuration, we were able to measure the subjects in the evening, but after sleeping from 6 to 7 hours, says Schrauwen. "Using glucose forceps and stable isotopes, we were able to accurately measure the insulin sensitivity of the liver and muscles, by taking muscle biopsies from the subjects, and then we studied the processes that were exactly affected in the muscle. "
The report states that this important finding may explain the increased risk of type 2 diabetes in night shift workers. The study therefore answers the question of whether a "24-hour economy" can have an effect on people's health. Disruptions in eating habits, obesity and the risk of developing cancer have also been linked to the growing violation of a natural sleep-wake cycle.
Biorhythm
During the reversal of the rhythm of day and night, something happened strikingly among the subjects. Researcher Jakob Wefers: "The biological clock is not just in our brain, but in every cell of our body. In our study, we discovered that this biological clock did not adapt to the new schedule; In muscle, we found that the molecular biological clock was still functioning in the olden days. This explains why the muscle also becomes less sensitive to insulin. And that may be another explanation for the increased risk of type 2 diabetes in people who work in shifts, "says Wefers.
Diabetes Type 2
In Type 2 Diabetes, the body no longer responds well to insulin is insulin is the hormone that regulates blood sugar levels.Insulin can not do its job and a consequence of this is that too much sugar stays in blood.First the body produces additional insulin, but after a while it becomes less and less.
Source link
