Nuts can help slow the growth of breast cancer: study



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One study says that eating nuts can help suppress the growth and survival of breast cancer.

The study, published in the journal Nutrition Research, found that consuming two ounces of nuts a day for about two weeks significantly altered gene expression in confirmed breast cancers.

"Nut consumption has slowed the growth of breast cancer and reduced the risk of breast cancer in mice," said W Elaine Hardman of Marshall University in the United States.

"Building on this research, our team hypothesized that walnut consumption would alter gene expression in pathologically confirmed breast cancers in women, in a direction that would decrease growth." and the survival of breast cancer, "said Hardman in a statement.

In this first clinical trial, women with breast mass large enough to support research and the biology of pathologies were recruited and randomized into nut or control consuming groups.

Immediately after the biopsy, women in the walnut group started consuming two ounces of nuts a day until follow-up surgery.

Pathological studies confirmed that the masses were breast cancer in all women who participated in the trial.

During surgery, approximately two weeks after the biopsy, additional samples were taken from breast cancers.

Changes in gene expression in the surgical specimen compared to baseline values ​​were determined in each woman, in nut consuming groups and control groups.

The expression profile of the RNA sequencing revealed that the expression of 456 genes identified was significantly altered in the tumor due to nut consumption.

The study has shown the activation of pathways that promote apoptosis or programmed cell death and cell adhesion and inhibition of pathways that promote cell proliferation and migration.

"These results support the hypothesis that, in humans, walnut consumption could inhibit the growth and survival of breast cancers," Hardman said.

"Further studies through a larger scale study would be needed to clinically confirm that walnut consumption actually reduces the risk of breast cancer or breast cancer recurrence," Hardman said.

(Media report entries)

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