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Pathology tests have a unique place in the management of chronic diseases. They are used to guide the management of the disease; assess risks and compliance; and enable the early detection of adverse events, complications and the development of secondary diseases. Primary care clinicians use guidelines for common chronic conditions such as type 2 diabetes, chronic kidney disease, and hypertension to know what tests to recommend to patients and how often. With pathology test rates rising, with an estimated annual cost of £ 1.8 billion for primary care in the UK1– and the potential for harm caused by over-testing, it is important to consider the evidence base for these recommendations.
In this article, we review the UK's current guideline surveillance strategies for patients with type 2 diabetes, chronic renal failure, and hypertension (Box 1), highlighting the uncertainties of these recommendations and the need for further research.
Research Strategy and Selection of Guidelines
We sought guidelines published in the UK for the management of patients with type 2 diabetes, chronic renal failure at stages 1 to 3 * or hypertension using the following sources:
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National Institute for the Excellence of Health and Care (NICE)
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Scottish Intercollegiate Guidelines Network (SIGN)
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Royal Colleges of Pathologists (RCPath), Physicians and GPs
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Quality Results Framework (QOF)
The following guidelines are included in this review:
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SIGN 116 Diabetes Management (2017)2
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NICE CG127 Hypertension, clinical management of primary hypertension in adults (2011)3
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NICE …
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