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Prostate cancer is now the most frequently diagnosed cancer in the UK, research shows. Data analyzed by the Prostate Cancer UK charity show that it has overtaken breast cancer to be the most commonly diagnosed form of the disease, with 57,192 new cases in 2018 – the most recent figures available. Worryingly, many have attributed a type of plastic that could increase the risk of developing the deadly disease. Bisphenol A, or BPA, is a common building block in resins and some types of plastics and is said to increase the risk of prostate cancer.
In 2006, Dr. Gail Prins, professor of urology and physiology at the College of Medicine at the University of Illinois at Chicago, and colleagues provided evidence for one of the first direct links between exposure to low dose to BPA during development of rats and subsequent development of prostate cancer.
“The most important results are that the human prostate epithelium responds in the same way as previous studies found in rodents,” Prins told the Cancer Network. The results show that even low doses of BPA can cause early and subtle changes that can have latent consequences.
“Our results indicate that these [stem] cells are epigenetically reorganized [upon exposure to BPA] in such a way that when they “see” estrogen later in life, the response is more robust, ”said Prins.
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Numerous studies have shown that BPA can interact with estrogen receptors and therefore up-regulate or down-regulate signaling pathways, said Olivier Sanchez, Founder of Nutrunity UK and Head of Nutrition at The Really Healthy Company.
He continued, “In fact, BPA is a weak estrogen, which makes it a hormone disruptor, like the thousands of chemicals widely used in plastics.
“Hormone disruptors can affect the way hormones work in the body, blocking their actions or mimicking them, which very often imbalances the fragile body’s hormonal balance.
“Therefore, BPA may play a role in the pathogenesis of several endocrine disorders, including female and male infertility, polycystic ovary syndrome (PCOS), and hormone-dependent tumors such as breast and prostate cancer. and several metabolic disorders, including.
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In a study published in the US National Library of Medicine, National Institutes of Health, bisphenol A as a risk factor for prostate cancer was studied in more detail.
The study noted: “Environmental exposures are contributing factors to the etiology of prostate cancer, but these remain unclear.
“We recruited 431 newly diagnosed prostate cancer cases and 402 controls of the same age at Prince of Wales Hospital in Hong Kong.
“We obtained clinical data and epidemiological information from each participant on chronic exposure to BPA and other environmental risk factors (eg, eating habits, occupation and shift work) using a standard questionnaire. “
The study concluded that frequent consumption of fried foods and pickled vegetables, unusual consumption of green tea, and night work are the risk factors contributing to prostate cancer among Chinese in Hong Kong.
More importantly, this study provides the first epidemiological evidence for the carcinogenicity of BPA in the human prostate.
Mr Sanchez added: “The problem here is not that BPA alone is capable of causing health problems or even prostate cancer, it is the constant, daily exposure and its tendency to bioaccumulate in our body, as well as the synergistic effect with the soup of the highly toxic chemicals to which we are exposed daily, which is of great concern for human health, especially since BPA can be considered cytotoxic (toxic to human cells, especially liver cells) and cause DNA damage.
“Global consumption of BPA by volume (in metric tons and USD) for different application areas is expected to reach 10.6 million metric tons in 2022.
“And so, our exposure to BPA continues to grow daily.
“This constant level of exposure cannot be innocent.”
BPA is banned in the UK and the EU from January 2020.
In a 2013 study by Professor Watson, there was evidence that exposure to BPA or BPS appeared to affect the timing of neural development.
The experts behind the findings warned to process receipts as little as possible and that the chemicals in BPA, found in almost all receipts, could be harmful.
BPS is currently not banned in the UK, although Switzerland is the first country to ban both BPS and BPA.
BPS is still available in the UK.
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