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German scientists have found that administering the AstraZeneca vaccine could potentially produce antibodies which in turn stimulate blood clots in “rare” cases, as the WHO does not see such a “causal” link.
A research team from the German University Hospital of Greifswald has discovered a mechanism that could lead to the development of sinus or cerebral vein thrombosis in patients who received the AstraZeneca vaccine.
The team received six blood samples from people with thrombosis after taking the vaccine. The samples were provided by the Paul Ehrlich Institute – the body responsible for the approval and control of all vaccines in Germany.
As a result of the analysis, researchers at Greifswald found that an immune response to the vaccine could involve the formation of antibodies that normally only form when an organism needs to heal a wound by blood clotting, reported the German channel NDR.
These antibodies then “Activate” platelets and may stimulate blood clots, especially in the venous sinuses of the brain.
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The team’s findings, which have not yet been published in any scientific journals, were then shared by the German Association for Thrombosis and Hemostasis Research (GTH), which released a new guideline for patients. receiving the vaccine.
According to the association’s statement, the Greifswald team found a “Significant pathological mechanism” but all the same noted that such a complication is “Specific and very rare.” He also said the finding does not rule out a situation in which thrombosis in patients who took the AstraZeneca jab was triggered by “Other causes”.
The GTH also said it has recorded at least 13 cases of sinus or cerebral vein thrombosis in people vaccinated with the AstraZeneca vaccine in Germany, including 12 women and a man between the ages of 20 and 63. All patients presented with similar symptoms which were probably caused by “Immunological event”, he added.
Greifswald’s team, meanwhile, also suggested targeted therapy for people with thrombosis after vaccination. However, it can only be applied after the appearance of blood clots and cannot be used as a preventive measure.
In light of the latest developments, the GTH has issued a new recommendation encouraging all people with continuous headaches, dizziness or vision disturbances more than three days after vaccination to undergo special screening to reduce the risk. develop thrombosis and obtain timely medical assistance.
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The news came as the World Health Organization (WHO) released its own statement on the safety of the AstraZeneca vaccine, claiming that the vaccine still has “A positive benefit-risk profile.” The United Nations health watchdog’s Global Advisory Committee on Vaccine Safety has reviewed data from Europe, the UK and India as well as its own global database and said it does not had not found “Any overall increase in coagulation conditions” linked to the vaccine.
WHO has also stated that it is not “certain” this “Very rare and unique thromboembolic events” such as cerebral venous sinus thrombosis “Were caused by vaccination.”
“No cause and effect relationship between these rare events has been established at this time,” It said.
German scientists are not the first to report a link between the AstraZeneca vaccine and thrombosis. Previously, similar conclusions had been presented by Norwegian specialists. However, the European Medicines Agency (EMA) again found the vaccine safe and effective on Thursday, after a week-long review.
The move prompted some European countries that had previously stopped using the vaccine due to concerns about its health risks to resume administration. German Chancellor Angela Merkel also said on Friday that she would do so “definitely” be vaccinated with the AstraZeneca jab.
The Chancellor spoke out in favor of using Russia’s Sputnik V vaccine if approved by the EU. If Brussels does not place any orders for the Russian jab after its approval, Berlin could very well do it on its own, she added.
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