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An exciting study revealed that a strain of colds had been successful in targeting and destroying cancerous bladder cells. Surprising results suggest that the common cold could revolutionize the future treatment of cancer.
Scientists from the University of Surrey and Royal Surrey County Hospital took a natural strain of the common cold virus, the Coxsackie virus (CVA21), and used it in 15 cancer patients with cancer. noninvasive bladder on the muscle. The disease is the 10th most common cancer in the UK.
Patients received CVA21 with a catheter in their bladder one week prior to surgery to remove their tumors.
By examining the samples after the surgery, the scientists found that the virus only targets cancer cells, infecting and then reproducing them, causing cancer cells to rupture and die. Urine specimens collected during the trial revealed "excretion" of the virus, indicating that the replicated virus continued to target and attack other cancer cells in the body.
NMIBC currently requires an intrusive and long treatment that is "Ineffective and toxic in a proportion of patients" Hardev Pandha explained.
The cold virus appears to inflame the tumor, causing immune cells to target and kill cancer cells. Normally, bladder tumors do not have immune cells and the body's immune system does not attack cancer.
The majority of patients' tumors had cell death, and in one patient, no trace of cancer was found during surgery after only one week of treatment. No significant side effects were observed in any of the patients.
"Oncolytic viruses such as the Coxsackie virus could transform the way we treat cancer and could indicate a move away from more traditional treatments such as chemotherapy", Nicola Annels, research fellow at the University of Surrey, said.
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