Scientists discover new breakthrough in treatment for cancer hair loss

Scientists have determined a new way to protect the hair follicle from chemotherapy in an effort to prevent hair loss.

Researchers at the University of Manchester have discovered a new strategy for preventing hair follicles from chemotherapy, which could lead to new treatments that prevent chemotherapy-induced hair loss-arguably one of the most psychologically distressing side effects of modern cancer therapy.

Published in the newspaper, EMBO Molecular Medicine, The study from the laboratory of the Ralf Paus of the Center for Dermatology Research, explains how to prevent hair loss, can be prevented.

To do this, CDK4 / 6 inhibitors, which blocks the field of drugs, have already been approved as "cancer therapies".

Dr. Talveen Purba, lead author on the study explains: "Although at first this counter-intuitive, we found that CDK4 / 6 inhibitors can be used to reduce the risk of stroke. organ-cultured human hair scalp follicles in CDK4 / 6 inhibitors, the hair follicles were much less likely to the damaging effects of taxanes "

Taxanes are very important anti-cancer drugs commonly used to treat, for example, patients with breast cancer and especially carcinoma causes. (Thousands of patients in the US are currently suing pharmaceutical companies.) Sanofi has a lack of warning of the risk of taxotere drug taxotere.

Dr. Purba emphasizes: "A pivotal part of our study is that we have the right to respond to the follicle of the patient." , and the stem cells from which they arise, are most vulnerable to taxanes, therefore, we must protect these cells most from undesired chemotherapy effects-but so that cancer does not benefit from it. "

The team hopes that their work will be scaled up to the extent that they will be successful. This could complement and enhance the effectiveness of existing preventive approaches i.e. scalp cooling devices.

The researchers underscored the desperately needed condition of this disease in the field of cancer medicine, where patients waited for long-term breakthroughs in pharmacological hair loss prevention.

Dr. Purba said: "Despite the fact that taxanes have been used in the clinic for decades, we have only been scratching the surface of what they do."

He added: "We also do not know what they are, but they do not know what they are doing, and why they are certain chemotherapy regimens and drug combinations.

"We need time to further develop prevention, but promote hair follicle regeneration in patients who have already lost their hair due to chemotherapy."