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WASHINGTON – A certain type of medicine used to treat diabetes may help manage the disease, but a study recommends doctors look for the worrying signs of a dangerous flesh infection in patients who take it, or even kill it.
According to USA Today, the study published in Annals of Internal Medicine examined the links between sodium glucose-cotransporter-2 inhibitors, used in the treatment of type 2 diabetes, and a genital infection called Fournier gangrene, an "extremely rare but potentially fatal" disorder. , according to the Food and Drug Administration, which examined 55 cases of infected patients.
All of these patients had taken SGLT2 inhibitors between March 2013 and January 2019. They all became "critically ill" and were released, noting that there had been hospitalizations, surgeries, and other complications. .
Three patients died of Fournier gangrene.
In comparison, when the researchers examined patients taking other types of anti-glycemic agents over a 35-year period, they identified only 19 cases of Fournier gangrene on the whole of this period, with two deaths noted.
Last year, the FDA had warned of symptoms of the disease, including "sensitivity, redness or swelling of the genitals or genital area up to the rectum", as well as Fever over 100.4 degrees and "a general feeling of discomfort". . "
The authors of the study advise physicians to pay attention to these signs in patients taking SGLT2 inhibitors and to have "a high index of suspicion to recognize them at an early stage".
(The man's necrotizing fasciitis caused him to lose much of his penis.)
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