When it comes to the organs you know you’re supposed to watch out for, your heart, brain, and colon are probably jumping to the top of your mind. Your pancreas? Not really.
But the end Peril! Host Alex Trebek drew needed attention to the neglected organ after announcing he had stage 4 pancreatic cancer in 2019. Trebek, who hosted Peril! since 1984, died Sunday morning at the age of 80.
Although pancreatic cancer is rarer than other forms of the disease, it is also among the deadliest. And the survival rate for stage 4 pancreatic cancer is particularly low. According to the American Cancer Society, an estimated 55,440 people will be diagnosed with pancreatic cancer in 2018, and 44,330 will die from it. According to the National Cancer Institute’s Surveillance, Epidemiology, and Outcomes (SEER) program, only about eight percent of all people with pancreatic cancer survive five years after initial diagnosis. The five-year survival rate for patients diagnosed with metastatic or stage 4 pancreatic cancer is 3%. Once patients are at this stage, the cancer has spread to other organs, such as the liver or lungs.
What is even scarier? Pancreatic cancer is difficult to detect and does not require routine screening. What’s more, it can also spread to other organs early on, says Daniel M. Labow, MD, FACS, chair of the Mount Sinai West and Mount Sinai St. Luke Department of Surgery, and chief of oncology. surgery and hepatobiliary surgery at Icahn. Mount Sinai School of Medicine.
Although not all people with pancreatic cancer have early symptoms, knowing what to watch out for can help doctors treat it as quickly as possible, which greatly increases your chances of survival. Here are eight possible signs of pancreatic cancer – some of which your doctor has probably never told you about.
1
Your skin and eyes are turning yellow.
Jaundice is the result of a buildup of bilirubin, or bile, in your bloodstream. The bile duct passes through the pancreas, so when cancer cells grow near the head of the pancreas, the tumor can compress the bile duct, which pushes bile back into the bloodstream.
When your skin and the whites of your eyes turn yellow, the true-colored pigment in bile passes through your blood, which is deposited in the skin and fat, says Dr. Labow. Other symptoms associated with jaundice are dark, Coca-Cola-colored urine and light, clayey stools, he adds. “Bilirubin in the gut is what makes the stool brown, and so when it recedes and enters the bloodstream, it can’t get into the gut,” he explains.
2
Greasy stools.
The pancreas plays an important role in fat digestion, says Dr. Labow. If the bile and pancreatic enzymes do not make their way to the intestines due to a blockage – for example, a tumor – undigested fat will increase the fat content of the stool, making it fatty. It might even float above the water in your toilet.
3
Pain in the back or stomach.
“The pancreas is located deep in the abdomen, so sometimes there is irritation to the nerves around the spine. [because of] the cancer is there, “says Dr Labow.” This can cause a stabbing pain in the upper mid back. “
Most of the time, it won’t be excruciating five-alarm pain. “Sometimes people feel like they are pulling back, and they think it will be better after a few days and it never really does,” he adds.
Pancreatic cancer can also cause pancreatitis, which is inflammation of the pancreas that can cause abdominal pain. You don’t have to have both back pain and abdominal pain – it could be either, Dr. Labow says.
4
Rapid and unexplained weight loss.
“Some cancers secrete [compounds] in the blood which can cause the body to break down, ”says Dr. Labow. This can lead to rapid weight loss due to the breakdown of fatty tissue and skeletal muscle. “Even if you eat non-stop, you won’t be able to gain or maintain weight,” says Dr. Labow.
While this applies to many types of cancer, there is another reason why pancreatic cancer in particular can lead to rapid weight loss. “You don’t absorb fat and protein like you normally would, so even if you eat well, you don’t necessarily absorb all of the calories you eat,” says Dr. Labow.
5
Nausea and vomiting.
Cancer in general can be linked to nausea and vomiting, but it is especially common with pancreatic cancer because of the important role the pancreas plays in digestion.
“The pancreas is located right next to the stomach and duodenum, which is the first part of the small intestine,” says Dr. Labow. “A large lump could push on it, which can affect the way food leaves the stomach and goes through the digestive tract. So your stomach may not empty like it normally does.”
6
A lump under the right side of your rib cage.
In some cases, you may be able to feel your gallbladder in the upper right quadrant of your abdomen, coming out from under your rib cage.
“An enlarged gallbladder can occur because of the way bile flows through the bile duct,” says Dr. Labow. “If the bile duct and gallbladder are blocked [as a result of pancreatic cancer], then it can sometimes make the gallbladder quite big and distended, and you can feel it. “
seven
A swollen, throbbing leg.
If one of your legs is swollen and painful, it could be a sign of deep vein thrombosis (DVT), which is a blood clot that forms in a vein deep in your body, usually in your leg.
“Cancer in general is known to increase the risk of blood clots in patients because cancer can [induce a hypercoagulable state], or something that causes you to clot abnormally, ”says Dr. Labow.
It becomes especially dangerous if a blood clot breaks off and travels to the lungs, called a pulmonary embolism, says Dr. Labow. “[Look for] any sudden shortness of breath for no good reason, or a prolonged rapid heart rate for no reason, “he says. Pulmonary embolism can be fatal, but it can be treated if you catch it, so get these symptoms checked right away.
While most of the above symptoms are usually not caused by pancreatic cancer, the old adage “prevention is better than cure” still applies. “Any symptom that doesn’t have a good explanation or persists for more than a few days should be investigated in one way or another,” says Dr Labow, even if it’s just a call for help. your doctor.
8
A diagnosis of diabetes
Although rare, pancreatic cancer can cause diabetes, according to the American Cancer Society. This is because the cancer destroys the insulin-producing cells. When this happens, people may feel more thirsty or hungry than normal. Some patients may be asymptomatic, but changes in blood sugar levels can be detected by blood tests.
Alexa tucker
Alexa is a Denver-based contributor covering everything related to lifestyle, wellness, travel, home, and beauty.
Melissa Matthews
Health editor
Melissa Matthews is the health writer at Men’s Health, which covers the latest in food, nutrition and health.
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