[ad_1]
Siegel, R.L., Miller, K.D. and Jemal, A. Cancer Statistics, 2017. CA Cancer J. Clin. 677-30 (2017).
Mann, K.M., Ying, H., Juan, J., Jenkins, N.A. and Copeland, N.G. KRAS-related proteins in pancreatic cancer. Pharmacol. Ther. 16829-42 (2016).
Pettazzoni, P. et al. Genetic events that limit the effectiveness of MEK and RTK inhibitor therapies in a mouse model of pancreatic cancer caused by KRAS. Cancer Res. 751091-1101 (2015).
Shimizu, T. et al. The clinical effect of double targeting strategy involving PI3K / AKT / mTOR and RAS / MEK / ERK pathways in patients with advanced cancer. Clin. Cancer Res. 18, 2316-232 (2012).
Kapoor, A. et al. The activation of Yap1 helps to bypass the oncogenic dependence on Kras in pancreatic cancer. Cell 158, 185-197 (2014).
Viale, A. et al. Pancreatic cancer cells resistant to oncogene ablation depend on mitochondrial function. Nature 514628-632 (2014).
Ying, H. et al. Oncogenic Kras maintains pancreatic tumors by regulating anabolic glucose metabolism. Cell 149, 656-670 (2012).
da Cunha, J.P. et al. Bioinformatic construction of the human cell surface. Proc. Natl Acad. Sci. United States 10616752-16757 (2009).
Binder, J. X. et al. COMPARTMENTS: unification and visualization of the evidence of subcellular localization of proteins. Database 2014, bau012 (2014).
Biankin, A.V. et al. The pancreatic cancer genomes reveal aberrations in the genes of the axonal guidance pathway. Nature 491399-405 (2012).
Capello, M. et al. The carboxylesterase 2 as a determinant of the response to irinotecan and neoadjuvant treatment by FOLFIRINOX in pancreatic ductal adenocarcinoma. J. Natl. Cancer Inst. 107, djv132 (2015).
Carugo, A. et al. In vivo A functional platform targeting patient-derived xenografts identifies the WDR5-Myc association as an essential determinant of pancreatic cancer. Cell reports 16133 to 147 (2016).
Alexander, C. M. et al. Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice. Nat. Broom. 25329-332 (2000).
Subramanian, S.V., Fitzgerald, M.L. and Bernfield, M. Regulated Excretion of Ectopecan-1 and -4 Ectopomains by Activation of Thrombin Receptors and Growth Factor. J. Biol. Chem. 27214713-14720 (1997).
Chen, K. & Williams, K. J. Molecular mediators for syndecan-1 raft-dependent endocytosis, a highly conserved multifunctional receptor. J. Biol. Chem. 28813988-13999 (2013).
Zimmermann, P. et al. Syndecan recycling is controlled by Syntenin – PIP2 interaction and Arf6. Dev. Cell 9377-388 (2005).
Robertson, S.E. et al. Extracellular signal-regulated kinase regulates endosomal trafficking independent of clathrin. Mol. Biol. Cell 17645-657 (2006).
Honda, A. et al. Phosphatidylinositol 4-phosphate 5-kinase α is a downstream effector of the small G ARF6 protein in the formation of membrane smears. Cell 99521-532 (1999).
Bar-Sagi, D. and Feramisco, J. R Induction of membrane fringing and pinocytosis in the fluid phase in resting fibroblasts by ras proteins. Science 2331061-1068 (1986).
Commisso, C. et al. Macropinocytosis of the protein is a pathway of amino acid supply in Ras transformed cells. Nature four hundred ninety seven633-637 (2013).
Brown, F., D., Rozelle, L., Yin, H., Balla, T., and Donaldson, J., Membrane trafficking regulated at phosphatidylinositol 4,5-bisphosphate and at Arf6. J. Cell Biol. 1541007-1017 (2001).
Radhakrishna, H., Klausner, R.D. and Donaldson, J.G. Aluminum fluoride stimulates surface protrusions in cells overexpressing ARF6 GTPase. J. Cell Biol. 134935-947 (1996).
Fujii, M., Kawai, K., Egami, Y. and Araki, N. Dissect the roles of activation and deactivation of Rac1 in macropinocytosis with the aid of microscopic photo-manipulation. Sci. Representative. 32385 (2013).
Su, G., Blaine, SA, Qiao, D. and Friedl, A. The excretion of syndecan-1 by stromal fibroblasts stimulates the proliferation of breast cancer cells in humans via l? activation of FGF2. J. Biol. Chem. 28214906-14915 (2007).
Langford, J.K., Yang, Y., Kieber-Emmons, T. and Sanderson, R.D. Identification of a regulatory domain of invasion within the syndecan-1 core protein. J. Biol. Chem. 280, 3467-3473 (2005).
Beekman, J.M. and Coffer, P.J.The ins and outs of syntenin, a multifunctional intracellular adapter protein. J. Cell Sci. 1211349-1355 (2008).
Taguchi, A. et al. The signatures of lung cancer in plasma are based on the proteomic profile of tumor models of mice. Cancer cell 20, 289-299 (2011).
Aguirre, A. J. et al. Kras activated and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma. Genes Dev. 17, 3112-3126 (2003).
Burbach, B.J., Friedl, A., Mundhenke, C. and Rapraeger, A.C. Syndecan-1 accumulate in lysosomes of poorly differentiated breast carcinoma cells. Matrix Biol. 22163-177 (2003).
Commisso, C., Flinn, R.J. and Bar-Sagi, D. Determination of Macropinocyte Index of Cells by a Quantitative Image-Based Assay. Nat. Protocol. 9, 182-192 (2014).
[ad_2]
Source link