Upon his return from a trip to Southeast Asia, a 54-year-old man experienced an increase in creatinine levels, suggesting kidney damage or dysfunction. After referring to a kidney specialist and other tests, it was discovered that a naturopath had prescribed him high doses of vitamin D, the latter having recommended him to take 8 drops a day. In two and a half years, the patient, who had no history of bone loss or vitamin D deficiency, took 8 to 12 drops of vitamin D per day, for a total of 8,000 to 12,000 IU. As a result, his blood calcium level was very high, which caused him significant kidney damage.
"Although the toxicity of vitamin D is rare because of a wide therapeutic range, its widespread availability in various over-the-counter formulations can pose a significant risk to uninformed patients," writes Dr. Bourne Auguste, researcher dialysis clinic at Toronto General. Hospital and the University of Toronto.
The recommended daily allowance is 400 to 1,000 IU, with 800 to 2,000 IU being recommended for adults at high risk of osteoporosis and for the elderly.
"Our experience tells us that patients and clinicians should be better informed about the risks associated with unhindered use of vitamin D. Given the new findings of the US Task Force on Preventive Services, it is important to review the current Canadian guidelines for its use in low-risk individuals, "the authors suggest.
"The use of vitamin D drops leading to kidney failure in a 54-year-old man" is published on April 8, 2019.
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- Bourne L. Auguste, Carmen Avila-Casado, Joanne M. Bargman. Use of vitamin D drops leading to kidney failure in a 54-year-old man. Journal of the Canadian Medical Association2019; 191 (14): E390 DOI: 10.1503 / cmaj.180465
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Journal of the Canadian Medical Association. "Too much good things? High doses of vitamin D can lead to kidney failure." ScienceDaily. ScienceDaily, April 8, 2019.
Journal of the Canadian Medical Association. (April 8, 2019). Too much of a good thing? High doses of vitamin D can cause kidney failure. ScienceDaily. Retrieved April 9, 2019 from www.sciencedaily.com/releases/2019/04/190408114319.htm.
Journal of the Canadian Medical Association. "Too much good things? High doses of vitamin D can lead to kidney failure." ScienceDaily. www.sciencedaily.com/releases/2019/04/190408114319.htm (accessed April 9, 2019).