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The trial, funded by Diabetes UK and led by experts from Newcastle University and the University of Glasgow, allowed patients to follow the Cambridge Weight Plan, a weight management program designed specifically for feeding. . Of the 298 participants with type 2 diabetes, 36% are in remission two years after the start of the trial. According to the latest study, the results confirm that the remission of type 2 diabetes is closely related to weight loss. Sixty-four percent of participants who lost more than 10 kg were still in remission after two years.
Patients regained weight between the first and second years, as expected, but those in remission after the first year who remained in remission had higher average weight loss than those who did not remain in remission.
Those who remained in remission after the first year lost 15.5 kg on average, while those who did not remain in remission lost an average of 12 kg.
The participants were defined as being in remission if they had a long-term blood glucose lower than 48 mmol / mol, without the need to take medication.
Ashley Evans of Norfolk was able to reverse the symptoms of his type 2 diabetes after losing five kilograms of weight.
"I developed type 2 diabetes after gaining a lot of weight following an accident," Ashley said.
"I was taking a lot of medicine and I felt constantly indisposed and lacked energy. My diabetes consultant explained to me that even if I lost only one stone, I could possibly reduce the medications that I was taking.
"But, like many people, I thought the drugs could help and continue to eat normally – chocolate, chips and take-aways.
"I took even more weight by buying bigger clothes and ignoring my diabetes.
"Meanwhile, I took a vacation to Jamaica. When I saw the pictures of myself, I was so shocked that I decided to do something about it. So, I looked for a diet that could start my weight loss.
"I discovered the 1: 1 diet of Cambridge Weight Plan and it's really the best thing I've done.
"With the support of my wonderful consultant, Mandy Smith, I lost five stones. As a result, I reversed the symptoms of my type 2 diabetes and no longer taking medication – my family doctor is absolutely delighted. "
Professor Anthony Leeds, Medical Director of the Cambridge Weight Plan, said, "It's great to see that type 2 diabetes can be reversed by significant weight loss.
"This follows another report showing that total diet replacement programs, combined with personalized support, are an effective and cost-effective way to lose weight over the long term.
"We have seen hundreds of people participating in our diet successfully reverse their type 2 diabetes while maintaining their weight loss.
"All thanks to a simple program of low-calorie milk products and the individual assistance of a consultant."
The results of the trial, called the Diarrhetic Remission Clinical Trial (DiRECT), were published in The Lancet Diabetes & Endocrinology.
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