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An experimental vaccine, developed 40 years ago by scientists, has been tested positive for Human Immunodeficiency Virus (AIDS) and has managed to protect the monkeys from infection. A study published in the medical journal Lancet.
Vaccine trials are moved to the next phase of experimental procedures prior to approval, after the drug has been shown to be safe in humans, and will be tested on 2,600 women in South Africa to discuss their ability to prevent AIDS.
Study researchers and experts from abroad warn that despite the encouraging results so far, there is no guarantee for the success of the drug in the next experimental phase called "HTNV705" (HTNV705) or "Imbukudu", meaning the rock in Zulu.
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Dan Barroch said, "Although the data is encouraging, we need to be more cautious."
"The success of the vaccine in protecting two-thirds of the monkeys in a laboratory experiment does not mean that it will protect humans," he told AFP. We must therefore wait for the results of the study before knowing if this will protect humans against AIDS. "
The results of Imbukudu research should be published in 2021 or 2022.
Efficacy in humans over the 35-year history of AIDS in the world."
A vaccine , called RV144, has shown some form of disease prevention. RIV 144 was announced in 2009 to reduce the risk of HIV infection by 31.2% among 16,000 Thai volunteers, but it was not enough to classify it as an antiviral drug
The nominee for 393 healthy AIDS-free adults ages 18 to 50 in East African countries and South Africa, Thailand and the United States.
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A group of vaccines or a placebo, and received four doses over 48 weeks.
The study used vaccine formulations called "mosaic vaccines".
These combinations combine different types of HIV to produce a response, at a time when the body attacks foreign germs, against viral strains in different parts of the world.
The vaccine "produced the most potent (high) immune response to humans."
Tests have shown that the vaccine is safe, but five participants reported side effects such as abdominal pain, diarrhea, dizziness or back pain. In a separate study, the drug itself proved the complete prevention of AIDS in two-thirds of adult monkeys. They were 72 test monkeys who had given six doses of a virus similar to AIDS.
Frankfurter Venter of the Utwatersrand University for Reproductive Health and AIDS Institute in South Africa urged scientists to be cautious. "It's a new drug in so many ways, so it's an exciting vaccine, but we still have a long way to go," he said.
Vaccine research In France, the vaccine will probably not be a "final" version, but it could represent "exceptional progress".
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About 1.8 Million People are infected with the disease and about a million die each year.
Infected 80 million people with HIV since the diagnosis of the disease for the first time in the early 1980s.
About 35 percent of it has died in the world up to now .
No drug has been shown to be effective. In cells and escape the immune system only to reappear and spread again after years. [19659005[LeVIH/SIDA] is currently the primary means of preventing sexual or blood transmission, but many prefer to use the treatment of inactivation of the virus as a preventive measure.
The latest study comes with the next International AIDS Conference to be held in Amsterdam from July 23rd to July 27th.
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