An anti-aging molecule prevents liver and kidney diseases



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NEW YORK (Reuters Health) – A new study suggests that scientists have discovered a way to increase the levels of an anti-aging molecule to protect the kidneys and liver from deterioration.

The study found that the concentration of an enzyme called NAD + decreases with age, and that restoring its normal level in the body can prolong health and age, which in turn is the subject of much research in the field of food science and medicine. And even the pharmaceutical field.

The functions of the human body require the proper functioning of the enzyme NAD +, enzyme aid present in all living cells and involved in metabolism and oxidative reactions.It transfers electrons from one reaction to another and plays a role in The series of internal respiration, which means that "adenosine duodenucleotide and nicotine", is strongly involved in the production of energy and keeps cells alive and healthy.

The enzyme was first identified in the early twentieth century, but scientists found that this molecule could actually cause muscle damage, but soon after, another study had revealed that adenosine and the nicotinic dynucleotide could treat Alzheimer's disease in mice.

But our inventory of this molecule is diminishing over time and scientists now think that this could be the key to aging.

The team of Swiss scientists seems to have found a way to replenish this stock in the kidneys and liver by blocking a compound that competes with its production through experiments on mice and worms, while clinical trials on the liver and kidney can be performed. have been indefinitely postponed to this stage.

Scientists from the Polytechnic Institute of Lausanne, Switzerland, have discovered a way to increase the production of enzymes in the body by blocking another enzyme called ACMSD, which limits its presence due to the amount of nicotine and anti-aging adenine.

ACMSD is found mainly in the liver and kidneys of mammals and would be involved in the development of diseases related to these organs in the body.

"Since the enzyme is found mainly in the kidneys and liver, we wanted to test the ability of ACMSD inhibitors to protect these organs from infection," said Dr. Elena Katsiuba, principal author of the study. "When scientists have blocked ACMSD in mice and worms, Regarding the patient, they found that they are very helpful in improving the condition of these members, which leaves a lot of hope for the therapeutic potential of the human being.

"The presence of ACMSD exclusively in the liver and kidneys reduces the risk of adverse effects on other organs and, considering the beneficial effects on health of the increase in the rates of Adenosine and nicotinic dichotonucleotides observed in models of worms and diseased mice, clinics for patients with liver and kidney diseases. "

Source: Daily Mail

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