Antibiotics in "childhood" cause the first type of diabetes

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"Alwan News"

The School of University of Washington medicine said that taking antibiotics, even for a session in early childhood, increases the risk of developing type 1 diabetes.

Researchers study living microbes in the intestines and play an important role in the immune system of children (microbium). The results showed that the number of children treated with antibiotics in their early childhood increases as the child is treated three times during the first two years of life. The number of people with type 1 diabetes has also doubled.

The researchers point out that the reason lies in the intestinal microbiome, where results from experiments in laboratory mice showed that the number of bacteria Enterococcus, Blautia, Enterobacteriaceae, Akkermansia in the intestines of the mice treated with antibiotics more than in the intestines of other mice. It seems that these bacteria contribute to the development of the autoimmune body, and therefore attack the cells of the pancreas, which causes the development of the first type of diabetes.

These results are confirmed by the results of screening children with type 1 diabetes, where they found that the number of these types of bacteria in their intestines much more than usual.

According to the researchers, the change in intestinal germination leads to an imbalance in the chemical compounds produced by bacteria, which affects the functioning of genes in the intestinal mucosa. These genes have been shown to stimulate immune cells that have a devastating effect on pancreatic cells.

From here, the researchers concluded that the use of antibiotics in the treatment of children whose immune system is not complete causes a change in their gut and increases the risk of pancreatic lesions, leading to the development of type 1 diabetes.