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Cambridge (Massachusetts): "Middle East"
There is a complex interplay between microbes in our intestines and between our organs, including the cardiovascular system, the nervous system and the immune system …
How billions of bacteria in the intestines play a role
While most health experts present the most popular trends in health research, they will most likely remember "microbiology".
– Living Organisms
Microbiome, the sum of living microbes with humans, also called "The intestinal bacterial flora. This term refers to the enormous number of microbes and microorganisms that are estimated per trillion and live in our bodies.
Dr. Joanne Manson, professor of medicine at Harvard Medical School and head of the Department of Preventive Medicine at Harvard University, says, "The most common bacteria, viruses and fungi live in our intestines, help to digestion, produce specific nutrients, Brigham and Women's Hospital: "There is a complex interplay between microbes in our intestines, our organs, including the cardiovascular system, the nervous system, the endocrine system and the system. immune. All of these interrelated relationships are very much related to cardiovascular health. "
– Results of Microbial Metabolism
As expected, what we eat is already playing a key role in the synthesis of microorganisms in our intestines, and we now know more about it. effect of substances produced by intestinal microbes on the risk of many chronic diseases, including diabetes, heart disease and cancer, as underlined by Dr. Manson.
One of the most popular metabolic products ( intestinal distillates) Trimethylamine (TMA), which forms when intestinal microbes feed on choline, a nutrient found in red meat, fish, poultry and eggs.The substance in the liver is converted to trimethylamine N-oxide (TMAO), which is closely related to the formation of platelets that cause arterial blockage
A study (published by Dr. Manson and colleagues in 2017 in the Journal of the Society) Ame Heart rican) The results of 19 studies have focused on the relationship between the level of methylmethylamine in the blood and the occurrence of serious cardiovascular problems, including heart attacks and strokes.
People who had high levels of methylmethylamine, with serious cardiovascular problems of 62% as well as high levels of the disease, high levels of death, and independent links to traditional factors such as diabetes, Obesity and kidney problems. A new target for prevention and treatment strategies.
Microorganisms in the intestine are also known to affect other factors associated with cardiovascular diseases such as diabetes, hypertension and inflammation. For example, a high fiber diet can stimulate the growth of intestinal bacteria that produce short chain fatty acids. The intestine containing these microbes seems to help diabetics to better control blood sugar and body weight, according to a limited study
– Regulation of Blood Pressure
Short-Chain Fatty Acids, The Intestines play a role in the regulation of blood pressure: studies in mice indicate that these fats are related to the expansion and contraction of blood vessels. This observation is one of many observations of a report on the role of microorganisms in the human body in the regulation of blood pressure, published in the September 2017 issue of the journal Hypertension.
Other Preliminary Results Discussed in
> How High Levels of Sodium in Food Modify the Composition of Microorganisms That Live in the Gut
How Toxic Substances Produced by Microbes May Affect the Gut Renal function, which plays a role in the regulation of blood pressure [19659003]> How live microbes interact with nitrates in vegetables To be nitrates and nitric oxide, which help to relax blood vessels.
However, this region is still emerging in its infancy, said Dr. Manson. More and more evidence suggests that dietary habits, which help prevent heart disease such as refraining from eating red meat, reduce salt intake and eat high fiber vegetables as well as grains whole, have positive effects on microorganisms.
> What about probiotics, that is live bacteria found in yogurt and other fermented foods and in dietary supplements? While these components are likely to improve the case of diarrhea caused by infection or antibiotics, and to relieve the symptoms of irritable bowel syndrome, evidence of its usefulness is still limited.
It's too early to recommend regular biologics to prevent or treat the most chronic diseases, said Dr. Manson. "In most cases, we do not know if biomarkers are reaching their target and microorganisms are changing," she says. Dr. Manson and other researchers in the United States have received numerous grants from the National Institutes of Health to study the science of metabolism to predict the risk of cardiovascular disease and diabetes.
– Harvard Heart Message, Tribune Media Services
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