Low doses of aspirin protect against ovarian cancer

Two new studies suggest that a single low dose of aspirin a day can help women avoid ovarian cancer or improve their survival.

In fact, the low daily dose of aspirin, which many older women take to help their heart, is associated with a 10% lower incidence of ovarian cancer. The researchers said that it was associated with up to 30% of survival cases for ovarian cancer patients.

Dr. Mitchell Kramer said: "It is clear that these two studies demonstrate the utility of using these anti-inflammatory drugs, and a glimpse of how to better prevent and treat this disease fatal. " He directs obstetrics and gynecology at the Huntington Hospital of North Hill Health in Huntington, New York.

Kramer did not participate in the new studies, and stated that "further studies are absolutely necessary." However, "the recommended low dose of 81mg aspirin can help prevent this disease, as well as women who have already contracted it.

Ovarian cancer is the fifth major killer of cancer, largely because of its late detection.

According to researchers, there is increasing evidence that inflammation plays a role in cancer development and may worsen the results. has been shown that drugs such as aspirin and non-steroidal nonsteroidal anti-inflammatory drugs – including ibuprofen (Motrin, Advil) or naproxen (ALF) – can be used to reduce the risk of Certain types of cancer.

But do these drugs have a role to play against ovarian tumors?
But did you know that researchers at the National Cancer Institute and the Moffitt Cancer Center in Tampa, Florida have collected data from 13 studies The studies involved more than 750,000 women and questioned them about their consumption of aspirin and NSAIDs. The researchers then followed these women – more than 3,500 women – to see who developed ovarian cancer. Do these drugs have a role to play against ovarian tumors?

According to the report, published July 18 in the Journal of the National Cancer Institute, daily intake of aspirin reduces the risk of ovarian cancer by 10%. "This study gives us a new perspective on whether NSAIDs and aspirin can affect the risk of cancer," said Shelley Toorogar, lead author of the study and director of the Center for Population Sciences at Moffitt Cancer Center. , at a press conference. "The results of the study support the ability of aspirin to reduce the risk of ovarian cancer," said Trowerger. "The results of the study support the ability of aspirin to reduce the risk of ovarian cancer, further studies should be conducted before a daily recommendation of aspirin. "

In a second study, researchers from the University of Hawaii in Honolulu and the Moffitt Cancer Center used nursing health studies to collect data on nearly 1,000 women who have already been diagnosed with ovarian cancer.

The researchers found that women who used aspirin and non-aspirin non-aspirin after their diagnosis of ovarian cancer had an improvement in their survival rate of 30%. To our knowledge, this study contributes to the first comprehensive evaluation of the use of several common analgesic drugs, such as aspirin and nonsteroidal anti-inflammatory drugs, according to Melissa Merritt, assistant research professor at the Center. oncology of the University of Hawaii. Ovarian Cancer "Our work demonstrates the importance of joint medicine in increasing survival rates for ovarian cancer, and this will encourage further studies to confirm the results and broaden the detection, "she said in a press release.

Both studies were based on retrospective observation data, so that they were unable to confirm the cause-and-effect relationship, which were only common.

Dr. Adi Davydov, who manages gynecology at the University of Staten Island University in New York, said that evidence of an effect appeared to exist.

The results are described as "interesting," and it is believed that "we can now add nonsteroidal anti-inflammatory drugs to reduce the risk of cancer."

"As aspirin has anti -Inflammatory side effects, looking for its benefits for this deadly disease means a lot. "

Source: https://www.webmd.com/ovarian-cancer/news/20180720/low-dose-aspirin-may-help-against-ovarian-cancer#2